1220516-07-3Relevant academic research and scientific papers
Synthesis of N-substituted carbazolones from α-iodo enaminones via Pd(0)-catalyzed intramolecular coupling under microwave irradiation
Yun, Xi-Liu,Bi, Wen-Ying,Huang, Jian-Hui,Liu, Yu,Zhang-Negrerie, Daisy,Du, Yun-Fei,Zhao, Kang
supporting information; experimental part, p. 5076 - 5080 (2012/09/25)
A variety of N-aryl and N-alkyl carbazolones were conveniently achieved in good to high yields via Pd2(dba)3-mediated intramolecular coupling of N-substituted α-iodo enaminones under microwave irradiation. The Pd(0)-catalyzed cyclization was found to proceed favorably with the more electron-deficient phenyl ring during the reactions involving unsymmetrical N,N-diaryl α-iodo enaminones. This unique property enables the construction of carbazolone skeleton containing nitro substituted benzenoid ring.
Concurrent α-iodination and N-arylation of cyclic β-enaminones
Chen, Yan,Ju, Tong,Wang, Junwei,Yu, Wenquan,Du, Yunfei,Zhao, Kang
supporting information; experimental part, p. 231 - 234 (2010/06/15)
A variety of N-substituted 3-aminocyclohex-2-enones were converted into the corresponding N-arylated α-iodo enaminones in high yields via concurrent N-iodination and N-arylation mediated by ArI(OAc)2. A mechanism is postulated to account for the reaction differences between the cyclic and the acyclic -enaminones, which undergo predominant β-acetoxylation under the same reaction conditions.
