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1220627-09-7

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1220627-09-7 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1220627-09-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,0,6,2 and 7 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 1220627-09:
(9*1)+(8*2)+(7*2)+(6*0)+(5*6)+(4*2)+(3*7)+(2*0)+(1*9)=107
107 % 10 = 7
So 1220627-09-7 is a valid CAS Registry Number.

1220627-09-7Downstream Products

1220627-09-7Relevant articles and documents

Discovery of Narrow Spectrum Kinase Inhibitors: New Therapeutic Agents for the Treatment of COPD and Steroid-Resistant Asthma

Onions, Stuart T.,Ito, Kazuhiro,Charron, Catherine E.,Brown, Richard J.,Colucci, Marie,Frickel, Fritz,Hardy, George,Joly, Kevin,King-Underwood, John,Kizawa, Yasuo,Knowles, Ian,Murray, P. John,Novak, Andrew,Rani, Anjna,Rapeport, Garth,Smith, Alun,Strong, Peter,Taddei, David M.,Williams, Jonathan G.

, p. 1727 - 1746 (2016/03/25)

The discovery of a novel series of therapeutic agents that has been designed and optimized for treating chronic obstructive pulmonary disease is reported. The pharmacological strategy was based on the identification of compounds that inhibit a defined subset of kinase enzymes modulating inflammatory processes that would be effective against steroid refractory disease and exhibit a sustained duration of action after inhaled delivery.

INHIBITORS OF HEMOPOIETIC CELL KINASE (P59-HCK) AND THEIR USE IN THE TREATMENT OF INFLUENZA INFECTION

-

, (2012/10/08)

The present invention relates inter alia to the treatment or prevention of influenza virus infection (including subtypes influenza A virus, influenza B virus, avian strain H5N1, A/H1N1, H3N2 and/or pandemic influenza) using compounds which inhibit the activity of p59-HCK and to a method of screening for a candidate drug substance intended to prevent or treat influenza virus infection in a subject, said method comprising identifying a test substance capable of inhibiting p59-HCK activity.

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