1221172-16-2

Basic information

• Product Name: 5-azido-2-chloro-6-(trifluoromethoxy)pyridine
• Synonyms: 5-azido-2-chloro-6-(trifluoromethoxy)pyridine
• CAS NO: 1221172-16-2
• Molecular Weight: 238.556
• Mol File: 1221172-16-2.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 5-azido-2-chloro-6-(trifluoromethoxy)pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 5-azido-2-chloro-6-(trifluoromethoxy)pyridine(1221172-16-2)
• EPA Substance Registry System: 5-azido-2-chloro-6-(trifluoromethoxy)pyridine(1221172-16-2)

Safety Data

• Hazardous Substances Data: 1221172-16-2(Hazardous Substances Data)

Upstream product

• 1221171-70-5 2-chloro-6-(trifluoromethoxy)pyridine 

Relevant articles and documents

A general approach to (trifluoromethoxy)pyridines: First X-ray structure determinations and quantum chemistry studies

The previously unknown 2-, 3-, and 4-(trifluoromethoxy)pyridines have now become readily accessible by means of an efficient and straightforward large-scale synthesis. Their regioselective functionalization by organometallic methods has been studied and has afforded new and highly important building blocks for life-sciences-oriented research. In addition, the first X-ray crystallographic structure determinations of (trifluoromethoxy)pyridines have been performed. Lowest-energy conformations of (trifluoromethoxy)pyridines and (trifluoromethoxy)pyridinium cations were determined by in silico studies. A general and efficient route to (trifluoromethoxy)pyridines is reported. Regioselective functionalization by organometallic methods afforded new and highly important building blocks for life-sciences-oriented research. The first X-ray crystallographic structure determinations of (trifluoromethoxy)pyridines have been performed and supported by in silico studies.