1221187-85-4Relevant articles and documents
Cu-catalyzed amidation of halogenated imidazoles
Wang, Mo,Zhang, Zhenfeng,Xie, Fang,Zhang, Wanbin
, p. 3163 - 3165 (2014)
An efficient methodology involving the Cu-catalyzed amidation of halogenated imidazoles has been successfully developed. The amidated product of 5-bromo-1-alkylimidazole was further applied to the synthesis of a new chiral imidazole nucleophilic catalyst for the kinetic resolution of secondary alcohols. The Royal Society of Chemistry 2014.
A double-ring structure with imidazole kind of chiral small organic molecular compound and its synthetic method
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Paragraph 0103; 0104; 0105, (2017/02/23)
The invention relates to an iminazole chiral organic micromolecule compound with a bicyclo-structure, as shown in chemical formula (I), and a synthesizing method thereof. The compound can be applied in various asymmetric reactions as a chiral catalyst, such as asymmetric acylation, asymmetric phosphorylation, asymmetric sulfonylation, asymmetric halogenate, asymmetric Micheal addition, asymmetricSteglich rearrangement reaction, asymmetric Morita-Baylis-Hillman reaction and the like. In addition, the compound also has potential bioactivities, such as anti-ulcer, anti-depression, antibiosis andenzyme inhibitory activities and the like.
