1221276-60-3

Basic information

• Product Name: C₁₉H₁₉BrN₂O₃
• Synonyms: C₁₉H₁₉BrN₂O₃
• CAS NO: 1221276-60-3
• Molecular Weight: 403.275
• Mol File: 1221276-60-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₉H₁₉BrN₂O₃(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₉H₁₉BrN₂O₃(1221276-60-3)
• EPA Substance Registry System: C₁₉H₁₉BrN₂O₃(1221276-60-3)

Safety Data

• Hazardous Substances Data: 1221276-60-3(Hazardous Substances Data)

Upstream product

• 22148-20-5 N-(4-bromophenyl)piperidine 
• 3156-43-2 2-[(E)-2-nitrovinyl]phenol 

Relevant articles and documents

Platinum-catalyzed michael addition and cyclization of tertiary amines with nitroolefins by dehydrogenation of α,β-sp3 C-H bonds

A mild platinum-catalyzed oxidative dehydrogenation of α,β- C(sp3)-H bonds of tertiary amines in the presence of ambient oxygen is revealed, and the in situ formed enamines subsequently reacting with various nitroolefins resulted in the development of two one-pot synthetic protocols involving Michael addition-elimination and Michael addition-cyclization. By using different functionalized nitroolefins compatible with the current oxidative conditions, two types of structurally divergent products, trisubstituted enamines and chromano[2,3-b]piperidines, could be expediently accessed, respectively.