122128-87-4Relevant academic research and scientific papers
COMPOUNDS AND COMPOSITIONS AS INHIBITORS OF CANNABINOID RECEPTOR 1 ACTIVITY
-
Page/Page column 69, (2008/06/13)
The invention provides compounds, pharmaceutical compositions comprising such compounds and methods of using such compounds to treat or prevent diseases or disorders associated with the activity of Cannabinoid Receptor 1 (CB1).
PROCESS FOR PRODUCING 3-UNSUBSTITUTED 5-AMINO-4-NITROSOPYRAZOLE COMPOUND, AND 2-HYDROXYIMINO-3-OXOPROPIONITRILE, 3-HYDRAZONO-2-HYDROXYIMINOPROPIONITRILE COMPOUND, AND PROCESSES FOR PRODUCING THESE
-
Page 11-12, (2010/02/09)
The present invention is to provide a process for preparing a 3-unsubstituted-5-amino-4-nitrosopyrazole compound represented by the formula (1):???wherein R1 represents a hydrogen atom, an alkyl group, an aryl group or a heterocyclic group each of which may have a substituent(s), which comprises cyclizing a 3-hydrazono-2-hydroxyiminopropionitrile compound represented by the formula (2):???wherein R1 has the same meaning as defined above, synthetic intermediates thereof and a process for preparing these intermediates.
3,3-DIALKOXY-2-HYDROXYIMINOPROPIONITRILES, PROCESS FOR PREPARATION THEREOF AND PROCESS OF PREPARING 5-AMINO -4-NITROSOPYRAZOLES OR SALTS THEREOF BY THE USE OF THE SAME
-
Page 10, (2008/06/13)
The present invention is to provide a 3,3-dialkoxy-2-hydroxyiminopropionitrile represented by the formula (1): ???wherein R1 and R2 may be the same or different from each other, and each represent an alkyl group having 1 to 8 carbon
A new efficient route to imidazo[4,5-c]pyrazol-5-ones
Vicentini, Chiara B.,Veronese, Augusto C.,Manfrini, Maurizio
, p. 629 - 632 (2007/10/03)
The synthesis of imidazo[4,5-c]pyrazol-5-ones (6) is reported. 5-Amino-4-ethoxycarbonylaminopyrazoles 3a-g when heated at 200°for 2 hours afford 6a-g. In a similar manner imidazo[4,5-c]pyrazol-5-one (6a) is readily obtained from 4-amino-5-ethoxycarbonylaminopyrazole (5a).
