122129-79-7 Usage
Uses
Used in Pharmaceutical Industry:
3,5-Difluoro-4-nitroaniline is used as an intermediate in the synthesis of various pharmaceuticals for its strong electron-withdrawing properties, which can enhance the activity and selectivity of the resulting compounds.
Used in Dye Industry:
3,5-Difluoro-4-nitroaniline is used as a building block in the production of dyes, where its unique chemical structure contributes to the color and properties of the final products.
Used in Agrochemical Industry:
3,5-Difluoro-4-nitroaniline is utilized as an intermediate in the synthesis of agrochemicals, such as pesticides and herbicides, due to its ability to improve the effectiveness and selectivity of these compounds.
Used in Organic Synthesis Research:
3,5-Difluoro-4-nitroaniline is employed as a versatile building block in organic synthesis research, where its strong electron-withdrawing properties can be exploited to develop new compounds with potential applications in various fields.
It is important to handle 3,5-difluoro-4-nitroaniline with caution, as it can be harmful if swallowed, inhaled, or comes into contact with the skin. Proper safety measures should be taken during its use to minimize potential risks.
Check Digit Verification of cas no
The CAS Registry Mumber 122129-79-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,1,2 and 9 respectively; the second part has 2 digits, 7 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 122129-79:
(8*1)+(7*2)+(6*2)+(5*1)+(4*2)+(3*9)+(2*7)+(1*9)=97
97 % 10 = 7
So 122129-79-7 is a valid CAS Registry Number.
InChI:InChI=1/C6H4F2N2O2/c7-4-1-3(9)2-5(8)6(4)10(11)12/h1-2H,9H2
122129-79-7Relevant academic research and scientific papers
Synthesis and Structural Investigation of Some Electron-Rich Nitroaromatics
White, Jonathan M.,Skene, Colin E.,Deadman, John,Epa, Ruwan,Foenander, Sarah,Hamer, Kyle,Fellowes, Thomas,Lim, Shea Fern,Marcuccio, Sebastian M.,Martin, Roger F.
, p. 311 - 327 (2019/02/07)
2,4-Difluoro-, 2,4,6-Trifluoro-, and 2,3,4,6,tetrafluoronitrobenzenes undergo nucleophilic aromatic substitution, once, twice, and three times with a variety of amine substituents with a high degree of regiochemical control to provide a range of electron-
REACTION OF AROMATIC COMPOUNDS WITH NUCLEOPHILIC REAGENTS IN LIQUID AMMONIA. X. AMINATION OF POLYFLUORINATED AROMATIC COMPOUNDS CONTAINING ELECTRON-WITHDRAWING SUBSTITUENTS
Selivanova, G. A.,Chuikova, T. V.,Shtark, A. A.,Shteingarts, V. D.
, p. 2267 - 2272 (2007/10/02)
It was shown for the case of 2,4-difluoro-, 2,4,6-trifluoro-, and pentafluoronitrobenzenes that both liquid ammonia and sodium amide in liquid ammonia are effective reagents for aminodefluorination with respect to the fluorine derivatives of nitrobenzene.The observed tendency for the ortho-orientation with respect to the nitro group to change to para-orientation with increase in the number of fluorine atoms is more clearly defined for sodium amide than for liquid ammonia as nucleophile on account, clearly, of the stabilization of the transition state of ortho-substitution in the latter case by an intramolcular hydrogen bond.
