1221497-75-1Relevant academic research and scientific papers
Facile assembly of H-pyrazolo[5,1-a]isoquinolines via silver triflate-catalyzed one-pot tandem reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and ketone or aldehyde
Yu, Xingxin,Ye, Shengqing,Wu, Jie
supporting information; experimental part, p. 2050 - 2056 (2010/11/04)
A novel and efficient route for the generation of H-pyrazolo[5,1-a] isoquinolines via silver triflate-catalyzed one-pot tandem reaction of 2-alkynylbenzaldehyde, sulfonohydrazide, and ketone or aldehyde is described. This reaction proceeds with good functional group tolerance under mild conditions with high efficiency and excellent selectivity.
Tandem reactions of N′-(2-Alkynylbenzylidene)hydrazides with Silyl Enolates: A facile route to H -pyrazolo[5,1- a ]isoquinolines
Yu, Xingxin,Chen, Zhiyuan,Yang, Xiaodi,Wu, Jie
experimental part, p. 374 - 378 (2010/09/11)
A silver triflate-catalyzed tandem reaction of N′-(2- alkynylbenzylidene)hydrazide with silyl enolate is described, which generates the unexpected H-pyrazolo[5,1-a]isoquinolines in good to excellent yields. Intramolecular cyclization, nucleophilic addition, condensation, and aromatization may be involved in the reaction process.
