1221576-43-7

Basic information

• Product Name: (2R,3R)-3-(adamantylthio)-2-hydroxy-3-phenylpropanoic acid
• Synonyms: (2R,3R)-3-(adamantylthio)-2-hydroxy-3-phenylpropanoic acid
• CAS NO: 1221576-43-7
• Molecular Weight: 332.464
• Mol File: 1221576-43-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2R,3R)-3-(adamantylthio)-2-hydroxy-3-phenylpropanoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: (2R,3R)-3-(adamantylthio)-2-hydroxy-3-phenylpropanoic acid(1221576-43-7)
• EPA Substance Registry System: (2R,3R)-3-(adamantylthio)-2-hydroxy-3-phenylpropanoic acid(1221576-43-7)

Safety Data

• Hazardous Substances Data: 1221576-43-7(Hazardous Substances Data)

Upstream product

• 115794-68-8 methyl (2S,3S)-phenylglycidate 
• 34301-54-7 1-Adamantanethiol 

Downstream Products

• 1221576-45-9 (2R,3R)-3-(adamantylthio)-3-phenylpropane-1,2-diol 

Relevant articles and documents

Phosphinite thioethers derived from chiral epoxides. Modular P, S -ligands for pd-catalyzed asymmetric allylic substitutions

A new family of modular P,S-ligands has been prepared from enantiopure arylglycidols. These ligands have been iteratively optimized with respect to four different structural parameters for use in Pd-catalyzed allylic substitutions. As a final output, highly active and enantioselective ligands for these synthetically important transformations have been developed, and the factors controlling their catalytic behavior have been rationalized. From a methodological point of view, a convenient procedure for the regioselective ring-opening of cis-glycidic esters with bulky thiols to yield the corresponding β-alkylthio-α-hydroxy carboxylic acids has been developed.