1221720-05-3

Basic information

• Product Name: (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene
• Synonyms: (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene
• CAS NO: 1221720-05-3
• Molecular Weight: 943.262
• Mol File: 1221720-05-3.mol

Chemical Properties

• CAS DataBase Reference: (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene(CAS DataBase Reference)
• NIST Chemistry Reference: (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene(1221720-05-3)
• EPA Substance Registry System: (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene(1221720-05-3)

Safety Data

• Hazardous Substances Data: 1221720-05-3(Hazardous Substances Data)

Upstream product

• 58645-35-5 3,4-O-isopropylidene-D-arabinopyranose 
• 189996-60-9 2,3-O-isopropylidene-D-erythrose 
• 1221720-04-2 (2'S,3'S,4'S)-1-(2,3,4-tri-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-5'-O-(tert-butyldimethylsilyl)-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene 
• 100-39-0 benzyl bromide 
• 1221720-03-1 2-(2,3-O-isopropylidene-4-O-(tert-butyldimethylsilyl)-1-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene 
• 1221720-02-0 1-(2,3-O-isopropylidene-4-O-(tert-butyldimethylsilyl)-1-trimethylsilylacetylene)-D-ribo-butan-1-ol 
• 174591-00-5 2,3-O-isopropylidene-1-trimethylsilylacetylene-D-ribo-butan-1,4-diol 

Downstream Products

• 1221720-07-5 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-heptadec-5',6'-enyl)-acetylene 
• 1221720-08-6 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-heptadecyl)-ethane 
• 1221720-10-0 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4';-O-isopropylidene-D-ribo-heptadecyl)-ethane 
• 1301629-45-7 (2'S,3'R,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-hexacosanoyl-D-ribo-heptadecyl)-ethane 
• 1301629-46-8 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(2'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane 
• 1301629-47-9 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(4'-O-hexacosanoyl-D-ribo-tetradecyl)-ethane 
• 1221720-06-4 (2'S,3'S,4'R)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-butyl)-acetylene 
• 1301629-44-6 (2'S,3'S,4'S)-1-(2,3,4,6-tetra-O-benzyl-α-C-D-galactopyranosyl)-2-(3',4'-O-isopropylidene-2'-O-(para-methoxybenzyl)-D-ribo-5'-carbaldehyde)-acetylene 

Relevant articles and documents

Use of the NEO strategy (Nucleophilic addition/Epoxide Opening) for the synthesis of a new C-galactoside ester analogue of KRN 7000

Our goal in the search for potentially bioactive analogues of KRN 7000 was to design an easy synthetic approach to a library of analogues using a strategy recently developed in our laboratory based on a Nucleophilic addition followed by an Epoxide Opening