1221922-49-1

Basic information

• Product Name: C₂₁H₂₂N₂O₃S
• Synonyms: C₂₁H₂₂N₂O₃S
• CAS NO: 1221922-49-1
• Molecular Weight: 382.483
• Mol File: 1221922-49-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₁H₂₂N₂O₃S(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₁H₂₂N₂O₃S(1221922-49-1)
• EPA Substance Registry System: C₂₁H₂₂N₂O₃S(1221922-49-1)

Safety Data

• Hazardous Substances Data: 1221922-49-1(Hazardous Substances Data)

Upstream product

• 1221931-54-9 ethyl 2-(6-phenylbenzo[d]thiazol-2-yl)acetate 
• 80945-86-4 6-bromo-2-chloro-benzothiazole 
• 791614-78-3 ethyl 2-(6-bromobenzo[d]thiazol-2-yl)acetate 
• 1221931-56-1 C₁₅H₁₀NO₂S^(1-)*Na⁽¹⁺⁾ 
• 27532-96-3 glycine tert-butyl ester hydrochloride 

Downstream Products

• 1221925-79-6 C₁₇H₁₄N₂O₃S 
• 1221918-45-1 C₁₉H₁₆N₄O₂S 

Relevant articles and documents

ACETIC ACID AMIDE DERIVATIVE HAVING INHIBITORY ACTIVITY ON VASCULAR ENDOTHELIAL LIPASE

Disclosed is a compound which is useful as an endothelial lipase inhibitor. A pharmaceutical composition having inhibitory activity on endothelial lipase comprising a compound represented by the formula: , its pharmaceutically acceptable salt, or a solvate thereof, wherein Ring A is nitrogen-containing hetero ring, Ring A may be substituted with a substituent other than a group represented by the formula: -C(R1R2)-C(=O)-NR3R4 and a group represented by the formula: -R5, a broken line represents the presence or the absence of a bond, Z is -NR6-, =N-, -O-, or -S-, R6 is halogen, substituted or unsubstituted alkyl or the like, R1 and R2 are each independently hydrogen, halogen, hydroxy, cyano, nitro, carboxy or substituted or unsubstituted alkyl, R3 is hydrogen or substituted or unsubstituted alkyl, R4 is hydrogen, substituted or unsubstituted alkyl or the like, R3 and R4 taken together with the adjacent nitrogen atom to which they are attached may form a substituted or unsubstituted ring, R5 is hydrogen, halogen, hydroxy, cyano, nitro, carboxy, substituted or unsubstituted alkyl, substituted or unsubstituted alkenyl, substituted or unsubstituted alkynyl or the like.