1221973-65-4Relevant academic research and scientific papers
Synthesis and antibacterial activity of bicyclic lactam-lactones
Angelov, Plamen,Hosamani, Kallappa M.,Jeong, Yong-Chul,Moloney, Mark G.,Thompson, Amber L.,Yaqoob, Muhammad
, p. 2181 - 2184 (2011)
The synthesis of a lactam-lactone bicyclic system containing a pyroglutamate subunit proceeds to give the fused lactone system, which is favoured over the spirocyclic lactone alternative. These systems display no or weak antibacterial activity against the
Oxazolomycins: Natural product lead structures for novel antibacterials by click fragment conjugation
Bagwell, Claire L.,Moloney, Mark G.,Yaqoob, Muhammad
scheme or table, p. 2090 - 2094 (2010/06/21)
Conjugation of amide and lactam subunits by a 'Click' type approach provides access to structural mimics of the oxazolomycin series of natural products, some of which exhibit antibacterial activity.
