1222102-51-3

Basic information

• Product Name: (R)-4-[(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(t-butoxymethyl)piperazin-2-one(tartrate)
• CAS NO: 1222102-51-3
• Molecular Weight: 551.517
• Mol File: 1222102-51-3.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: (R)-4-[(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(t-butoxymethyl)piperazin-2-one(tartrate)(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-4-[(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(t-butoxymethyl)piperazin-2-one(tartrate)(1222102-51-3)
• EPA Substance Registry System: (R)-4-[(R)-3-amino-4-(2,4,5-trifluorophenyl)butanoyl]-3-(t-butoxymethyl)piperazin-2-one(tartrate)(1222102-51-3)

Safety Data

• Hazardous Substances Data: 1222102-51-3(Hazardous Substances Data)

Usage

Uses

Evogliptin Tartrate is a useful intermediate used in the preparation of dipeptidyl peptidase-IV inhibitors and derivatives for the treatment of type 2 diabetes.

Upstream product

• 83480-29-9 voglibose 
• 147-71-7 D-tartaric acid 
• 657-24-9 dimethylbiguanide 
• 1246961-47-6 (R)-benzyl 3-(tert-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butyrate 
• 1246961-49-8 (R)-methyl 2-(2-(benzyloxycarbonylamino)ethylamino)-3-t-butoxypropanoate 
• 1246961-45-4 (R)-t-butyl 3-(t-butoxycarbonylamino)-4-(2,4,5-trifluorophenyl)butanoate 
• 936630-57-8 (R)-3-amino-4-phenyl(2,4,5-trifluorophenyl)butanoic acid 
• 881995-73-9 3-(R)-tert-butoxycarbonylamino-4-(2,4,5-trifluorophenyl)butyric acid methyl ester 
• 93204-37-6 (2R)-2-(benzyloxycarbonylamino)-3-tert-butoxypropionic acid methyl ester 
• 88132-89-2 (2R)-2-amino-3-tert-butoxypropionic acid methyl ester 
• 486460-00-8 (3R)-3-[(1,1-dimethylethoxycarbonyl)amino]-4-(2,4,5-trifluorophenyl)butanoic acid 
• 87-69-4 L-Tartaric acid 

Relevant articles and documents

PHARMACEUTICAL COMPOSITION FOR PREVENTION AND TREATMENT OF DIABETES OR OBESITY COMPRISING A COMPOUND THAT INHIBITS ACTIVITY OF DIPEPTIDYL PEPTIDASE-IV, AND OTHER ANTIDIABETIC OR ANTIOBESITY AGENTS AS ACTIVE INGREDIENTS

The present invention relates to a pharmaceutical composition for the prevention and treatment of diabetes or obesity comprising as active ingredients a compound which inhibits the activity of dipeptidyl peptidase-IV(DPP-IV), a pharmaceutically acceptable

METHOD FOR PREPARING DIPEPTIDYL PEPTIDASE-IV INHIBITOR AND INTERMEDIATE

The present invention relates to an improved method for preparing dipeptidyl peptidase-IV inhibitor and intermediate. The present invention is able to reduce preparation costs by using low cost reagents on reaction and is able to be used in mass production by improving yield.