1222379-83-0

Basic information

• Product Name: C₆₃H₆₇N₂O₁₀P
• CAS NO: 1222379-83-0
• Molecular Weight: 1043.21
• Mol File: 1222379-83-0.mol

Chemical Properties

• CAS DataBase Reference: C₆₃H₆₇N₂O₁₀P(CAS DataBase Reference)
• NIST Chemistry Reference: C₆₃H₆₇N₂O₁₀P(1222379-83-0)
• EPA Substance Registry System: C₆₃H₆₇N₂O₁₀P(1222379-83-0)

Safety Data

• Hazardous Substances Data: 1222379-83-0(Hazardous Substances Data)

Upstream product

• 1222379-80-7 C₅₄H₅₀O₉ 
• 124482-92-4 2-cyanoethyl-N,N-(diisopropylamino)chlorophosphine 

Relevant articles and documents

Specific induced circular dichroism and enhanced B to Z transitions of duplexes stabilized by chromophore-linked alkynylnucleoside residues

We have developed an induced circular dichroism (ICD) probe with a chromophore-linked alkynyldeoxyribose skeleton for analyzing higher-order structures of DNA duplexes in the visible-light region. When CG-repeated oligonucleotides (ODNs) with the probe at their 5' ends adopted Z-form duplexes at a high NaCl concentration, strong ICD signals were observed at the absorptive region of the chromophore. On the other hand, their B-form duplexes, formed at a low NaCl concentration, produced a faint ICD signal. The specific ICD for the Z-form duplexes was found to appear only when the chromophores were attached at the 5' ends of each of the ODNs. Furthermore, the chromophoric alkynylnucleoside residues effectively promoted the B to Z transition of the ODN.