122243-33-8

Basic information

• Product Name: Ethanone, 2,2,2-trifluoro-1-[4-(methylthio)phenyl]- (9CI)
• Synonyms: Ethanone, 2,2,2-trifluoro-1-[4-(methylthio)phenyl]- (9CI)
• CAS NO: 122243-33-8
• Molecular Formula: C₉H₇F₃OS
• Molecular Weight: 220.2114896
• Product Categories: ACETYLHALIDE
• Mol File: 122243-33-8.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 263.8°Cat760mmHg
• Flash Point: 113.3°C
• Appearance: /
• Density: 1.32g/cm³
• Vapor Pressure: 0.0101mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: Ethanone, 2,2,2-trifluoro-1-[4-(methylthio)phenyl]- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Ethanone, 2,2,2-trifluoro-1-[4-(methylthio)phenyl]- (9CI)(122243-33-8)
• EPA Substance Registry System: Ethanone, 2,2,2-trifluoro-1-[4-(methylthio)phenyl]- (9CI)(122243-33-8)

Safety Data

• Hazardous Substances Data: 122243-33-8(Hazardous Substances Data)

Usage

InChI:InChI=1/C9H7F3OS/c1-14-7-4-2-6(3-5-7)8(13)9(10,11)12/h2-5H,1H3

Upstream product

• 1073-72-9 4-hydroxythioanisole 
• 81290-20-2 (trifluoromethyl)trimethylsilane 
• 3446-89-7 4-(Methylthio)benzaldehyde 
• 122035-81-8 2,2,2-trifluoro-1-(4'-methylsulfanylphenyl)ethanol 
• 100-68-5 methyl-phenyl-thioether 
• 360-92-9 N,N-diethyl-2,2,2-trifluoroacetamide 
• 104-95-0 (4-bromophenyl)thioanisole 
• 18620-04-7 4-thioanisolemagnesium bromide 
• 407-25-0 trifluoroacetic anhydride 
• 353-85-5 trifluoroacetonitrile 

Downstream Products

• 122035-81-8 2,2,2-trifluoro-1-(4'-methylsulfanylphenyl)ethanol 
• 166831-86-3 2,2,2-trifluoro-1-(4-methylsulfanyl-phenyl)-ethanone oxime 
• 1096375-81-3 (R)-2,2,2-trifluoro-1-(4-methyltiophenyl)-1-(1H-pyrrol-2-yl)ethanol 

Relevant articles and documents

Access to Aryl and Heteroaryl Trifluoromethyl Ketones from Aryl Bromides and Fluorosulfates with Stoichiometric CO

We report a sequential one-pot preparation of aromatic trifluoromethyl ketones starting from readily accessible aryl bromides and fluorosulfates, the latter easily prepared from the corresponding phenols. The methodology utilizes low pressure carbon monoxide generated ex situ from COgen to generate Weinreb amides as reactive intermediates that undergo monotrifluoromethylation affording the corresponding aromatic trifluoromethyl ketones (TFMKs) in good yields. The stoichiometric use of CO enables the possibility for accessing 13C-isotopically labeled TFMK by switching to the use of 13COgen.

Oxime derivatives and the use thereof as latent acids

Compounds of formula I, II and III, wherein wherein R1is for example hydrogen, C1-C12alkyl, C3-C30cycloalkyl, C2-C12alkenyl, C4-C8cycloalkenyl, phenyl, whic

A simple and efficient preparation of 3-aryl-3-trifluoromethyl-3H-diazirinyl sulfoxides and sulfones

All regioisomers of 3-aryl-3-trifluoromethyl-3H-diazirinyl sulfoxides and sulfones have been prepared in five steps from the corresponding bromothioanisoles in excellent overall yields. The key step involves a simultaneous oxidation of sulfide and diaziri