122253-67-2

Basic information

• Product Name: 3-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridine
• CAS NO: 122253-67-2
• Molecular Weight: 685.954
• Mol File: 122253-67-2.mol

Chemical Properties

• CAS DataBase Reference: 3-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridine(122253-67-2)
• EPA Substance Registry System: 3-{(Z)-2-[(2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-yl]-vinyl}-4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridine(122253-67-2)

Safety Data

• Hazardous Substances Data: 122253-67-2(Hazardous Substances Data)

Upstream product

• 7152-15-0 ethyl 4-methyl-3-oxo-pentanoate 
• 1608-51-1 4-fluorochalcone 
• 122252-56-6 β-(4-fluorophenyl)-α-(2-methyl-1-oxopropyl)-δ-oxobenzenepentanoic acid, ethyl ester 
• 122252-70-4 4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinecarboxylic acid, ethyl ester 
• 122253-00-3 4-(4-fluorophenyl)-2-(1-methylethyl)-6-phenyl-3-pyridinemethanol 
• 122253-23-0 3-Bromomethyl-4-(4-fluoro-phenyl)-2-isopropyl-6-phenyl-pyridine 
• 86030-96-8 (2S,4R,6R)-4-(tert-Butyl-diphenyl-silanyloxy)-6-methoxy-tetrahydro-pyran-2-carbaldehyde 
• 122287-13-2 [4-(4-Fluoro-phenyl)-2-isopropyl-6-phenyl-pyridin-3-ylmethyl]-triphenyl-phosphonium; bromide 

Relevant articles and documents

Synthesis and Biological Activity of New HMG-CoA Reductase Inhibitors. 1. Lactones of Pyridine- and Pyrimidine-Substituted 3,5-Dihydroxy-6-heptenoic (-heptanoic) Acids

Lactones of pyridine- and pyrimidine-substituted 3,5-dihydroxy-6-heptenoic (-heptanoic) acids 2-4 have been synthesized.Extensive exploration of structure-activity relationships led to several compounds exceeding the inhibitory activity of mevinolin (1b)