1222558-13-5Relevant articles and documents
Synthesis of 1,3,5-triazinane-2-thiones and 1,3,5-oxadiazinane-4-thiones linked with isoxazoles
Rajanarendar,Siva Rami Reddy,Shaik, Firoz Pasha
experimental part, p. 119 - 122 (2010/04/29)
Trimolecular condensation of N-(3,5-dimethyl-4-isoxazolyl)N′- arylthioureas 2 obtained from 1 by reaction with arylisothiocyanates, with aqueous formaldehyde and primary amines in toluene under reflux leads to 5-alkyl-1-(3,5-dimethyl-4-isoxazolyl)-3-aryl-hexahydro-1,3,5-triazinane-2- thiones 3 in excellent yields. Condensation of 2 with aqueous formaldehyde under similar condition provides isoxazolyl 1,3,5-oxadiazinane-4thiones 4.