122323-87-9 Usage
Uses
Used in Pharmaceutical Industry:
2-HYDROXYMETHYL-PIPERAZINE-2HCl is used as a synthetic intermediate for the preparation of 4-substituted 1-(Arylacetyl)-2-[(dialkylamino)methyl]piperazines. These compounds are a highly selective and potent class of κ-opioid receptor agonists, which have potential applications in the treatment of pain and other medical conditions related to the opioid system.
Check Digit Verification of cas no
The CAS Registry Mumber 122323-87-9 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,3,2 and 3 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 122323-87:
(8*1)+(7*2)+(6*2)+(5*3)+(4*2)+(3*3)+(2*8)+(1*7)=89
89 % 10 = 9
So 122323-87-9 is a valid CAS Registry Number.
122323-87-9Relevant academic research and scientific papers
A potent new class of κ-receptor agonist: 4-Substituted 1-(arylacetyl)- 2-[(dialkylamino)methyl]piperazines
Naylor,Judd,Lloyd,Scopes,Hayes,Birch
, p. 2075 - 2083 (2007/10/02)
The synthesis of 4-substituted 1-(arylacetyl)-2- [(alkylamino)methyl]piperazines (10-22, 26, 27, and 30-33) and their activities as κ-opioid receptor agonists are described. This includes a range of 4-acyl and 4-carboalkoxy derivatives with the latter ser
