1223593-73-4 Usage
General Description
(E)-tert-butyl 2-(4-(3-(hydroxyaMino)-3-oxoprop-1-en-1-yl)benzoyl)hydrazinecarboxylate, also known as Rucaparib, is a chemical compound used in the treatment of ovarian cancer. It belongs to the class of PARP inhibitors, which work by preventing cancer cells from repairing their damaged DNA, leading to their death. Rucaparib has been approved for use in patients with advanced ovarian cancer who have received prior chemotherapy treatment and have a specific genetic mutation known as BRCA. It is typically administered orally and has shown promising results in clinical trials, making it a valuable option for patients with this type of cancer. The chemical structure of (E)-tert-butyl 2-(4-(3-(hydroxyaMino)-3-oxoprop-1-en-1-yl)benzoyl)hydrazinecarboxylate plays a crucial role in its therapeutic effects and mode of action.
Check Digit Verification of cas no
The CAS Registry Mumber 1223593-73-4 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,3,5,9 and 3 respectively; the second part has 2 digits, 7 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1223593-73:
(9*1)+(8*2)+(7*2)+(6*3)+(5*5)+(4*9)+(3*3)+(2*7)+(1*3)=144
144 % 10 = 4
So 1223593-73-4 is a valid CAS Registry Number.
1223593-73-4Relevant articles and documents
CLASS- AND ISOFORM-SPECIFIC HDAC INHIBITORS AND USES THEREOF
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Page/Page column 96, (2011/02/24)
HDAC inhibitors of the general formula (I) and (II) and pharmaceutically acceptable salts thereof, as described herein, are useful as inhibitors of histone deacetylases or other deacetylases, and thus are useful for the treatment of various diseases and d
