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12236-29-2

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12236-29-2 Usage

Properties and Applications

Yellow, red light yellow, yellow orange. Used for polyester, vinegar fiber, three vinegar fiber, polyamide fiber dyeing, levelness and promote good rate. Standard Ironing Fastness Light Fastness Persperation Fastness Washing Fastness Fading Stain Fading Stain Fading Stain ISO 4-5 3-4 7 5 5 5 5

Standard

Ironing Fastness

Fading

Stain

ISO

4-5

Check Digit Verification of cas no

The CAS Registry Mumber 12236-29-2 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,2,2,3 and 6 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 12236-29:
(7*1)+(6*2)+(5*2)+(4*3)+(3*6)+(2*2)+(1*9)=72
72 % 10 = 2
So 12236-29-2 is a valid CAS Registry Number.
InChI:InChI=1/C17H16N2O/c1-19(2)13-9-7-12(8-10-13)11-16-17(20)14-5-3-4-6-15(14)18-16/h3-11,18H,1-2H3

12236-29-2Relevant articles and documents

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Abramovitch,Marko

, p. 131,132,134,135 (1960)

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Design, synthesis and investigation of water-soluble hemi-indigo photoswitches for bioapplications

Berdnikova, Daria V.

, p. 2822 - 2829 (2019/12/11)

A series of hemi-indigo derivatives was synthesized and their photoswitching properties in aqueous medium were studied. The dimethoxy hemi-indigo derivative with the best photochromic performance in water was identified as a promising platform for the dev

Probing the Azaaurone Scaffold against the Hepatic and Erythrocytic Stages of Malaria Parasites

Carrasco, Marta P.,Machado, Marta,Gon?alves, Lídia,Sharma, Moni,Gut, Jiri,Lukens, Amanda K.,Wirth, Dyann F.,André, Vania,Duarte, Maria Teresa,Guedes, Rita C.,dos Santos, Daniel J. V. A.,Rosenthal, Philip J.,Mazitschek, Ralph,Prudêncio, Miguel,Moreira, Rui

, p. 2194 - 2204 (2016/10/19)

The potential of azaaurones as dual-stage antimalarial agents was investigated by assessing the effect of a small library of azaaurones on the inhibition of liver and intraerythrocytic lifecycle stages of the malaria parasite. The whole series was screened against the blood stage of a chloroquine-resistant Plasmodium falciparum strain and the liver stage of P. berghei, yielding compounds with dual-stage activity and sub-micromolar potency against erythrocytic parasites. Studies with genetically modified parasites, using a phenotypic assay based on the P. falciparum Dd2-ScDHODH line, which expresses yeast dihydroorotate dehydrogenase (DHODH), showed that one of the azaaurone derivatives has the potential to inhibit the parasite mitochondrial electron-transport chain. The global urgency in finding new therapies for malaria, especially against the underexplored liver stage, associated with chemical tractability of azaaurones, warrants further development of this chemotype. Overall, these results emphasize the azaaurone chemotype as a promising scaffold for dual-stage antimalarials.

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