122408-84-8Relevant academic research and scientific papers
5-HT3 receptor agonist, novel thiazole derivative and intermediate thereof
-
, (2008/06/13)
A 5-HT3 receptor against containing a thiazole derivative as the effective ingredient is provided and is represented by the Formula (I): STR1 wherein the A ring is substituted or unsubstituted and represents a benzene or a heterocyclic ring with one or two heteroatoms; one of L1 or L2 represents a single bond and the other is non-existent or represents an alkylene or alkenylene group; R represents: STR2
Certain optically active substituted α,α-dialkyl-pyrrolidine-3-methamines useful as intermediates
-
, (2008/06/13)
Optically pure isomers of 7-[3-(1,1-dialkylmethyl-1-amino)-1 -pyrrolidinyl[quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacter
Certain optically active substituted 3-pyrraidine acetic acid derivatives useful as intermediates
-
, (2008/06/13)
Optically pure isomers of 7-[3-(1,1-dialkylmethyl-1-amino)-1-pyrrolidinyl]quinolones and naphthyridones as therapeutically active and safe antibacterial agents are described, as well as pharmaceutical compositions thereof, and a method of treating bacteri
GABA Agonists and Uptake Inhibitors. Synthesis, Absolute Stereochemistry, and Enantioselectivity of (R)-(-)- and (S)-(+)-Homo-β-proline
Nielsen, Lone,Brehm, Lotte,Krogsgaard-Larsen, Povl
, p. 71 - 77 (2007/10/02)
The cyclic analogue of 4-aminobutyric acid (GABA), 3-pyrrolidineacetic acid (homo-β-proline), is a potent agonist at GABAA receptors, it interacts effectively with GABA-uptake mechanisms, and it is a moderately potent inhibitor of GABAB/s
