1224508-90-0

Basic information

• Product Name: 3,3-dimethylbutyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
• Synonyms: 3,3-dimethylbutyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate
• CAS NO: 1224508-90-0
• Molecular Weight: 441.955
• Mol File: 1224508-90-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 3,3-dimethylbutyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate(CAS DataBase Reference)
• NIST Chemistry Reference: 3,3-dimethylbutyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate(1224508-90-0)
• EPA Substance Registry System: 3,3-dimethylbutyl 2-(1-(4-chlorobenzoyl)-5-methoxy-2-methyl-1H-indol-3-yl)acetate(1224508-90-0)

Safety Data

• Hazardous Substances Data: 1224508-90-0(Hazardous Substances Data)

Upstream product

• 624-95-3 3,3-dimethylbutanol 
• 53-86-1 [1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid 

Relevant articles and documents

Peripheral site acetylcholinesterase inhibitors targeting both inflammation and cholinergic dysfunction

The design and study of two classes of noncompetitive acetylcholinesterase inhibitors (AChEIs) which also function as NSAID prodrugs are reported. The most potent AChEIs disclosed contain an aromatic alkyl-aryl linker between an NSAID and a lipophilic choline mimic and they inhibit acetylcholinesterase (AChE) in the submicromolar range. These agents have the therapeutic potential to dually target inflammation by releasing an NSAID in vivo and activating the cholinergic anti-inflammatory pathway via cholinergic up-regulation.