1224596-73-9Relevant academic research and scientific papers
Annelation reactions of pentafluorobenzonitrile
Cargill, Matthew R.,Linton, Katharine E.,Sandford, Graham,Yufit, Dmitrii S.,Howard, Judith A.K.
, p. 2356 - 2362 (2010)
Annelation reactions between pentafluorobenzonitrile and N,N-dimethylethylene diamine and 3-methyl picoline gave [6,6]-bicyclic and [6,5,6]-tricyclic ring-fused systems, respectively. Reaction of 4-morpholino tetrafluorobenzonitrile with hydrazine and phenyl hydrazine gave [5,6] ring-fused systems arising from a tandem SNAr and cyclisation process involving annelation onto the pendant cyano group providing an indication of the synthetic possibilities for heterocycle formation using the pentafluorobenzonitrile scaffold.
