122483-60-7Relevant academic research and scientific papers
2-Cyclopentadienylglycine, a new α-amino acid and its use for η5-complex formation
Dialer, Harald,Steglich, Wolfgang,Beck, Wolfgang
, p. 4855 - 4861 (2001)
The reaction of α-bromohippuric acid methyl ester with nickelocene, cyclopentadienylthallium or cyclopentadienyltrimethylsilane afforded N-benzoyl-2-cyclopentadienylglycine methyl ester (1) as two double bond isomers 1a and 1b. Similarly, the cyclopentadi
Generation of α-Acetoxyglycine Residues within Peptide Chains: A New Strategy for the Modification of Oligopeptides
Apitz, Gregor,Jaeger, Martin,Jaroch, Stefan,Kratzel, Martin,Schaeffeler, Lothar,Steglich, Wolfgang
, p. 8223 - 8232 (2007/10/02)
Seryl and threonyl peptides are converted into α-acetoxyglycyl peptides by treatment with lead tetraacetate.Reaction of these acetoxy derivatives or the more reactive α-chloroglycyl peptides with thiols, dithiols and carbohydrates allows the attachment of
CONVERSION OF SERINE AND THREONINE RESIDUES INTO α-ACYLOXY-, α-ALKYLTHIO-, AND α-HALOGENOGLYCINE MOIETIES: A NEW STRATEGY FOR THE MODIFICATION OF PEPTIDES
Apitz, Gregor,Steglich, Wolfgang
, p. 3163 - 3166 (2007/10/02)
Selective modification of serine and threonine containing peptides is accomplished by oxidation with lead tetraacetate.Conversion of the derived α-acetoxyglycine derivative into α-alkylthio- and α-halogenoglycine residues offers a novel synthetic route to
