1224849-38-0

Basic information

• Product Name: 2-methyl-1-(((4-nitrophenoxy)carbonyl)oxy)propyl propionate
• Synonyms: 2-methyl-1-(((4-nitrophenoxy)carbonyl)oxy)propyl propionate
• CAS NO: 1224849-38-0
• Molecular Weight: 311.291
• Mol File: 1224849-38-0.mol

Chemical Properties

• CAS DataBase Reference: 2-methyl-1-(((4-nitrophenoxy)carbonyl)oxy)propyl propionate(CAS DataBase Reference)
• NIST Chemistry Reference: 2-methyl-1-(((4-nitrophenoxy)carbonyl)oxy)propyl propionate(1224849-38-0)
• EPA Substance Registry System: 2-methyl-1-(((4-nitrophenoxy)carbonyl)oxy)propyl propionate(1224849-38-0)

Safety Data

• Hazardous Substances Data: 1224849-38-0(Hazardous Substances Data)

Upstream product

• 478296-54-7 1-chloro-2-methylpropyl(4-nitrophenyl)carbonate 
• 802294-64-0 propionic acid 
• 1224849-37-9 1-iodo-2-methylpropyl 4-nitrophenyl carbonate 
• 5489-14-5 silver⁽¹⁺⁾ propionate 

Relevant articles and documents

Pharmaceutical composition for the treatment or prevention of stroke and systemic embolism

The present invention relates to a prodrug useful for treating or preventing a stroke and systemic embolism and suitable for being effectively used in the oral delivery of dabigatran, and to a compound represented by chemical formula 1, a pharmaceutically acceptable salt thereof, and a hydrate thereof or a solvate thereof. The compound represented by the chemical formula 1, the pharmaceutically acceptable salt thereof, and the hydrate thereof or the solvate thereof are useful for treating or preventing a stroke and systemic embolism, and is suitable for being effectively used in oral delivery since the absorption rate, that is, bioavailability of dabigatran is improved.(AA) DSC curve of dabigatran pivoxyl (+)-(1S)- campo-10-sulfonateCOPYRIGHT KIPO 2015

COMPOUND HAVING TAFIA INHIBITORY ACTIVITY

Provided are compounds having superior TAFIa inhibitory activity. Specifically, there are provided compounds represented by the following formula (I) or pharmaceutically acceptable salts thereof: wherein A is a benzene ring or a pyridine ring; X is the formula -(CH2)-, the formula -(CH2)2-, an oxygen atom, a nitrogen atom or a single bond; Y is the formula -(CH2)3-NH-R3, the formula -(CH2)4-NH-R3 or a 2-aminopyridyl group; R3 is a hydrogen atom, a C1-6 alkyl group, or the formula -CO2R4; R4 is a C1-6 alkyl group, the formula -CHR5OC(O)R6, or a substituent having the structure represented by the following formula Ia; R5 is a C1-6 alkyl group; R6 is a C1-6 alkyl group, a C3-8 cycloalkyl group, or a phenyl group; R7 is a C1-6 alkyl group or a phenyl group; a R1 is a hydrogen atom, a halogen atom, a C1-4 alkyl group substituted by 1-3 halogen atoms, a C1-10 alkyl group, a C1-8 alkoxy group, a C3-8 cycloalkyl group, a C3-8 cycloalkoxy group, a C4-14 cycloalkylalkyl group, or a phenyl group; R2 is CO2R8, or a tetrazolyl group; R8 is a hydrogen atom, a C1-10 alkyl group, or a substituent having the structure represented by the following formula Ib or Ic; m and n are each an integer of zero or one.