1224870-53-4

Basic information

• Product Name: 4-{4-[4-(3-Iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-benzoic acid ethyl ester
• Synonyms: 4-{4-[4-(3-Iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-benzoic acid ethyl ester
• CAS NO: 1224870-53-4
• Molecular Weight: 568.454
• Mol File: 1224870-53-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4-{4-[4-(3-Iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-benzoic acid ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-{4-[4-(3-Iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-benzoic acid ethyl ester(1224870-53-4)
• EPA Substance Registry System: 4-{4-[4-(3-Iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidin-1-yl}-benzoic acid ethyl ester(1224870-53-4)

Safety Data

• Hazardous Substances Data: 1224870-53-4(Hazardous Substances Data)

Upstream product

• 451-46-7 4-fluorobenzoic acid ethyl ester 
• 35944-64-0 3-iodo-4-methylaniline 
• 1224872-09-6 4-[4-(3-iodo-4-methyl-phenylcarbamoyl)-phenyl]-piperidine-1-carboxylic acid tert-butyl ester 
• 149353-75-3 4-(1-(tert-butoxycarbonyl)piperidin-4-yl)benzoic acid 

Relevant articles and documents

Diacylglycerol Acyltransferase Inhibitors

Provided herein are compounds of the formula (I): were R1 is phenyl, R2 is hydrogen, halogen or lower alkyl, X is carbon on nitrogen, and R3 is isoquinoline, -amino, or a 4- to 6-membered heterocycloalkyl ring and pharmaceutically acceptable salts thereof, which are active as DGAT inhibitors and therefore find uses in treatment of diseases associated with abnormal metabolism of triglicerides such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.