122497-17-0Relevant academic research and scientific papers
A direct approach to the synthesis of famciclovir and penciclovir
Choudary, Bernadette M.,Geen, Graham R.,Kincey, Peter M.,Parratt, Martin J.,Dales, J. Robert M.,Johnson, Graham P.,O'Donnell, Steven,Tudor, David W.,Woods, Neil
, p. 981 - 994 (2007/10/03)
Reaction of 2-amino-6-chloropurine with triethyl 3-bromopropane-1,1,1- tricarboxylate followed by decarbethoxylation/transsesterification of the unpurified product was the key sequence in sythesising both the anti- herpesvirus agent penciclovir and its form famciclovir in three isolated steps.
