1225-43-0

Basic information

• Product Name: 17-BETA-HYDROXY-5-ALPHA-ANDROSTANE
• Synonyms: 5-ALPHA-ANDROSTAN-17-BETA-OL;17-BETA-HYDROXY-5-ALPHA-ANDROSTANE;5-A-androstan-17-B-ol;5ALPHA-Androstan-17B-ol;5α-Androstan-17β-ol;17β-Hydroxy-5α-androstane
• CAS NO: 1225-43-0
• Molecular Formula: C₁₉H₃₂O
• Molecular Weight: 276.46
• Mol File: 1225-43-0.mol
• Article Data: 12

Chemical Properties

• Melting Point: 163 °C
• Boiling Point: 375.9°Cat760mmHg
• Flash Point: 158.4°C
• Appearance: /
• Density: 1.019g/cm³
• Vapor Pressure: 3.44E-07mmHg at 25°C
• Refractive Index: 1.527
• PKA: 15.10±0.60(Predicted)
• CAS DataBase Reference: 17-BETA-HYDROXY-5-ALPHA-ANDROSTANE(CAS DataBase Reference)
• NIST Chemistry Reference: 17-BETA-HYDROXY-5-ALPHA-ANDROSTANE(1225-43-0)
• EPA Substance Registry System: 17-BETA-HYDROXY-5-ALPHA-ANDROSTANE(1225-43-0)

Safety Data

• Hazardous Substances Data: 1225-43-0(Hazardous Substances Data)

Usage

General Description

17-Beta-Hydroxy-5-Alpha-Androstane is a naturally occurring steroid hormone that is a derivative of androstane. It is a metabolite of testosterone and is involved in various physiological processes in the body. This chemical plays a crucial role in the development and maintenance of male reproductive tissues and is also important for the development of secondary sexual characteristics in males. Additionally, 17-Beta-Hydroxy-5-Alpha-Androstane has been studied for its potential use in hormone replacement therapy and as a treatment for various medical conditions related to hormonal imbalances. Overall, this chemical has significant implications for the functioning of the male reproductive system and has potential therapeutic applications in medicine.

InChI:InChI=1/C19H32O/c1-18-11-4-3-5-13(18)6-7-14-15-8-9-17(20)19(15,2)12-10-16(14)18/h13-17,20H,3-12H2,1-2H3/t13-,14+,15+,16+,17+,18+,19+/m1/s1

Upstream product

• 963-74-6 5alpha-androstan-17-one 
• 848-62-4 allopregnan-20-one 
• 20612-47-9 3β-chloro-5α-androstan-17-one 
• 148773-59-5 3α-(phenylthio)androstan-17-one 
• 71-41-0 pentan-1-ol 
• 1236-49-3 5α-androstan-17β-acetate 
• 17291-32-6 Toluene-4-sulfonic acid (8R,9S,10R,13S,14S,17S)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl ester 
• 17291-32-6 Toluene-4-sulfonic acid (8R,9S,10R,13S,14S,17R)-10,13-dimethyl-hexadecahydro-cyclopenta[a]phenanthren-17-yl ester 
• 6197-90-6 17β-acetoxy-androst-5-ene 
• 6960-01-6 3β-chloro-androst-5-en-17β-ol 
• 1229-09-0 3-chloroandrosta-3,5-dien-17-one 
• 3214-78-6 (17β)-androsta-3,5-dien-17-yl acetate 
• 2602-86-0 (17β)-androsta-3,5-dien-17-ol 
• 91-22-5 quinoline 

Downstream Products

• 17291-32-6 5α-androstan-17β-yl-4-toluenesulfonate 
• 54482-41-6 17-oxa-5α-androstan-16-one 
• 963-74-6 5alpha-androstan-17-one 
• 6301-86-6 17β-Propionyloxy-5α-androstan 
• 963-74-6 (5α)-androstan-17-one 
• 133832-44-7 5α-androstanyl formylbenzoate 
• 18899-47-3 5α-Androstan-17β-yl-trimethylsilylaether 
• 96191-85-4 benzoic acid-(5α-androstanyl-(17β)-ester) 
• 1236-49-3 5α-androstan-17β-acetate 

Relevant articles and documents

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Ultrasound assisted zinc reactions in synthesis 2. A new Clemmensen-type reduction

A mild and efficient method is described for the reduction of carbonyls to methylene groups. Under ultrasonic irradiation, deoxygenation of 3-oxosteroids with zinc dust in acetic acid or acetic acid/water was achieved in 15 minutes. The observed selectivity at C-3 in the presence of 17- and 20-oxo groups is discussed.

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Identification of a fossil sterane biomarker in crude oil - An androstane with a modified carbon skeleton

Three constitutional isomers of androstane were prepared for comparison with three unknown fossil C19H32 organic biomarkers ("19A", "19B", and "19C" in elution order in geological samples from Oman. 3β-Methyl-A-nor-androstane was pre

Factors Affecting the Facial Selectivity in the Hydroboration of Steroidal Δ5-Enes

A comparison between the facial selectivity observed in the hydroboration of some androst-5-enes and B-norandrost-5-enes does not parallel the differences between the calculated force field energies of α- and β-cyclobutane models suggesting that in this case the facial selectivity is not determined by the four centre transition state but by the ease of formation of the initial ?-complexes between the alkene and the borane.