1225055-55-9

Basic information

• Product Name: (8R,9S,13S,14S,17S)-2-(4-methoxyphenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
• Synonyms: (8R,9S,13S,14S,17S)-2-(4-methoxyphenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
• CAS NO: 1225055-55-9
• Molecular Weight: 378.511
• Mol File: 1225055-55-9.mol

Chemical Properties

• CAS DataBase Reference: (8R,9S,13S,14S,17S)-2-(4-methoxyphenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (8R,9S,13S,14S,17S)-2-(4-methoxyphenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(1225055-55-9)
• EPA Substance Registry System: (8R,9S,13S,14S,17S)-2-(4-methoxyphenyl)-13-methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol(1225055-55-9)

Safety Data

• Hazardous Substances Data: 1225055-55-9(Hazardous Substances Data)

Upstream product

• 5720-07-0 4-methoxyphenylboronic acid 
• 24381-12-2 2-Iodoestradiol 

Relevant articles and documents

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Cytochrome P450 (CYP) 1B1 is involved in the bioactivation of procarcinogens and drug resistance. To obtain selective CYP1B1 inhibitors over CYP1A1, we synthesized four series of estrane derivatives: (1) 12 estrone (E1)- and 17β-estradiol (E2)-derivatives

Mild arming and derivatization of natural products via an In(OTf) 3-catalyzed arene iodination

Figure presented Iodination of arene-containing natural products employing N-iodosuccinimide catalyzed by In(OTf)3 at ambient temperature is reported as a versatile and mild method for natural product derivatization amenable to small scale. This process facilitates natural product derivatization of arene moieties for SAR studies, homo- and heterodimerization of natural products, and also conjugation with reporters such as biotin via subsequent metal-mediated coupling reactions.