1225385-93-2Relevant academic research and scientific papers
MFA zeotype catalyst: A greener approach for the synthesis of INH azomethine scaffolds
Raghuvanshi, Devendra S.,Mahulikar, Pramod P.,Meshram, Jyotsna S.
, p. 48071 - 48078 (2015)
Herein, we are reporting the green and efficient synthesis of some pharmacologically important azomethine derivatives of isoniazide (INH) using Modified Fly Ash (MFA) as an excellent zeotic solid acid catalyst. The catalyst, by virtue of its terminal hydr
Acylhydrazones as Widely Tunable Photoswitches
Van Dijken, Derk Jan,Kova?í?ek, Petr,Ihrig, Svante P.,Hecht, Stefan
supporting information, p. 14982 - 14991 (2015/12/08)
Molecular photoswitches have attracted much attention in biological and materials contexts. Despite the fact that existing classes of these highly interesting functional molecules have been heavily investigated and optimized, distinct obstacles and inherent limitations remain. Considerable synthetic efforts and complex structure-property relationships render the development and exploitation of new photoswitch families difficult. Here, we focus our attention on acylhydrazones: a novel, yet underexploited class of photochromic molecules based on the imine structural motif. We optimized the synthesis of these potent photoswitches and prepared a library of over 40 compounds, bearing different substituents in all four crucial positions of the backbone fragment, and conducted a systematic study of their photochromic properties as a function of structural variation. This modular family of organic photoswitches offers a unique combination of properties and the compounds are easily prepared on large scales within hours, through an atom-economic synthesis, from commercially available starting materials. During our thorough spectroscopic investigations, we identified photoswitches covering a wide range of thermal half-lives of their (Z)-isomers, from short-lived T-type to thermally stable P-type derivatives. By proper substitution, excellent band separation between the absorbance maxima of (E)- and (Z)-isomers in the UV or visible region could be achieved. Our library furthermore includes notable examples of rare negative photochromic systems, and we show that acylhydrazones are highly fatigue resistant and exhibit good quantum yields.
A colorimetric and fluorescent chemosensor for the detection of an explosive-2,4,6-trinitrophenol (TNP)
Peng, Yu,Zhang, Ai-Jiang,Dong, Ming,Wang, Ya-Wen
supporting information; experimental part, p. 4505 - 4507 (2011/06/19)
A fluorescent and colorimetric receptor (L) for specific recognition of TNP was described. The origins of this remarkable affinity was disclosed by the crystal structure of corresponding host-guest complex L·TNP.
