122584-18-3 Usage
Description
N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide, with the CAS number 122584-18-3, is an off-white solid compound that is utilized in the field of organic synthesis. Its unique chemical structure contributes to its potential applications in various industries.
Uses
Used in Organic Synthesis:
N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide is used as a synthetic intermediate for the development of various organic compounds. Its chemical properties allow it to be a valuable building block in the creation of complex molecules, which can be further utilized in different applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide is used as a key component in the synthesis of new drugs. Its unique structure can be exploited to design and develop novel therapeutic agents with potential applications in treating various diseases.
Used in Chemical Research:
N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide is also used in chemical research as a model compound to study various reaction mechanisms and to understand the behavior of similar molecules. This knowledge can be applied to develop new synthetic methods and improve existing ones.
Used in Material Science:
In the field of material science, N-(p-Hydroxyphenethyl)-N-(2-bromo-5-hydroxy-4-methoxybenzyl)formamide can be used as a precursor to develop new materials with specific properties. Its unique chemical structure can be tailored to create materials with desired characteristics, such as improved stability, reactivity, or selectivity.
Flammability and Explosibility
Notclassified
Check Digit Verification of cas no
The CAS Registry Mumber 122584-18-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,2,5,8 and 4 respectively; the second part has 2 digits, 1 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 122584-18:
(8*1)+(7*2)+(6*2)+(5*5)+(4*8)+(3*4)+(2*1)+(1*8)=113
113 % 10 = 3
So 122584-18-3 is a valid CAS Registry Number.
InChI:InChI=1/C17H18BrNO4/c1-23-17-9-15(18)13(8-16(17)22)10-19(11-20)7-6-12-2-4-14(21)5-3-12/h2-5,8-9,11,21-22H,6-7,10H2,1H3
122584-18-3Relevant articles and documents
Development of a pilot scale process for the anti-alzheimer drug (-)-galanthamine using large-scale phenolic oxidative coupling and crystallisation-induced chiral conversion
Kueenburg, Bernhard,Czollner, Laszlo,Frohlich, Johannes,Jordis, Ulrich
, p. 425 - 431 (1999)
(-)-Galanthamine has been synthesised using an efficient nine-step procedure, which in large scale affords 12.4 (6.7-19.1)% overall yield. The process improvements and optimization of each step are described. Notable steps include (i) an oxidative phenol coupling and (ii) crystallisation-induced chiral conversion of (±)-narwedine to (-)-narwedine. This is a practical and cost-effective synthesis of (-)-galanthamine which is amenable to pilot plant scale-up to afford sufficient material for use in clinical trials.
Processes for the preparation of derivatives of 4a, 5, 9, 10, 11, 12-hexahydro-6H-benzofuro-[3a, 3, 2-ef][2]benzazepine
-
Example 9, (2008/06/13)
The invention relates to processes for the preparation of 4a,5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine, or derivatives thereof. Furthermore, the invention also relates to the compounds formed during the preparation of 4a, 5,9,10,11,12-hexahydro-6H-benzofuro[3a,3,2-ef][2]benzazepine.
An improved synthesis of galanthamine
Szewczyk,Lewin,Carroll
, p. 1809 - 1811 (2007/10/02)
Modifications in the total synthesis of the Amarylidaceae alkaloid of galanthamine from commercially available isovanillin and tyramine have resulted in a shortened reaction sequence, which is amenable to upscaling and in improved product yield.
