122641-10-5

Usage

Uses

Used in Pharmaceutical Industry:
1-(2-Morpholinoethyl)-2-thiourea is used as an active pharmaceutical ingredient for the development of different pharmaceutical products, leveraging its ability to inhibit nitric oxide synthase and potentially offering therapeutic benefits in various medical conditions.
Used in Scientific Research:
1-(2-Morpholinoethyl)-2-thiourea is used as a research tool in studies focused on cardiovascular, immunological, and neurological systems. Its impact on nitric oxide levels makes it a valuable compound for investigating the roles of nitric oxide in these systems and for exploring potential treatments for related disorders.
Used in Drug Delivery Systems:
In the context of drug delivery, 1-(2-Morpholinoethyl)-2-thiourea may be employed as a component in the design of drug delivery systems, potentially enhancing the efficacy and targeted delivery of therapeutic agents by modulating nitric oxide levels in the body.

InChI:InChI=1/C7H15N3OS/c8-7(12)9-1-2-10-3-5-11-6-4-10/h1-6H2,(H3,8,9,12)

Upstream product

• 63224-35-1 2-morpholinoethyl isothiocyanate 
• 90746-30-8 4-(2-aminoethyl)morpholine hydrochloride 

Downstream Products

• 1160623-91-5 2,5-difluoro-N-(3-(5-(2-((3-fluoro-4-(methyloxy)phenyl)amino)-4-pyrimidinyl)-2-((2-(4-morpholinyl)ethyl)amino)-1,3-thiazol-4-yl)phenyl)benzamide 
• 1160622-84-3 2,6-difluoro-N-(3-(2-((2-(4-morpholinyl)ethyl)amino)-5-(2-((2-(trifluoroacetyl)-1,2,3,4-tetrahydro-7-isoquinolinyl)amino)-4-pyrimidinyl)-1,3-thiazol-4-yl)phenyl)benzamide 
• 1551600-87-3 C₂₈H₃₁N₃O₅S 

Relevant academic research and scientific papers

ANTIVIRAL COMPOUNDS AND USE THEREOF

The present invention relates to compounds of formula (I), their use as medicaments, in particular as broad spectrum antiviral agents, their combination with a further antiviral agent and relative pharmaceutical compositions. In particular, the compounds of the invention are useful in the treatment of a disease caused by an enveloped virus.

Continuous-flow processing of gaseous ammonia using a Teflon AF-2400 tube-in-tube reactor: Synthesis of thioureas and in-line titrations

A simple tube-in-tube reactor based on the gas-permeable membrane Teflon AF-2400 was used in the continuous flow reaction of gaseous ammonia with isothiocyanates and one isocyanate. A colourimetric in-line titration technique is also reported as a simple method to quantify the amount of ammonia taken up by the solvent in the system. Georg Thieme Verlag Stuttgart · New York.

Synthesis of thiophene-2-carboxamidines containing 2-aminothiazoles and their biological evaluation as urokinase inhibitors

The serine protease urokinase (uPa) has been implicated in the progression of both breast and prostate cancer. Utilizing structure based design, the synthesis of a series of substituted 4-[2-amino-1,3-thiazolyl]-thiophene-2-carboxamidines is described. Further optimization of this series by substitution of the terminal amine yielded urokinase inhibitors with excellent activities.