1226549-45-6Relevant articles and documents
Discovery of a Furanopyrimidine-Based Epidermal Growth Factor Receptor Inhibitor (DBPR112) as a Clinical Candidate for the Treatment of Non-Small Cell Lung Cancer
Lin, Shu-Yu,Chang Hsu, Yung,Peng, Yi-Hui,Ke, Yi-Yu,Lin, Wen-Hsing,Sun, Hsu-Yi,Shiao, Hui-Yi,Kuo, Fu-Ming,Chen, Pei-Yi,Lien, Tzu-Wen,Chen, Chun-Hwa,Chu, Chang-Ying,Wang, Sing-Yi,Yeh, Kai-Chia,Chen, Ching-Ping,Hsu, Tsu-An,Wu, Su-Ying,Yeh, Teng-Kuang,Chen, Chiung-Tong,Hsieh, Hsing-Pang
, p. 10108 - 10123 (2019)
Epidermal growth factor receptor (EGFR)-targeted therapy in non-small cell lung cancer represents a breakthrough in the field of precision medicine. Previously, we have identified a lead compound, furanopyrimidine 2, which contains a (S)-2-phenylglycinol