1226710-09-3

Basic information

• Product Name: C₂₅H₂₆ClFN₄O₂
• CAS NO: 1226710-09-3
• Molecular Weight: 468.958
• Mol File: 1226710-09-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₅H₂₆ClFN₄O₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₅H₂₆ClFN₄O₂(1226710-09-3)
• EPA Substance Registry System: C₂₅H₂₆ClFN₄O₂(1226710-09-3)

Safety Data

• Hazardous Substances Data: 1226710-09-3(Hazardous Substances Data)

Upstream product

• 1226710-01-5 C₁₉H₂₁ClFN₃O 
• 188554-13-4 2-hydroxypyridine-4-carboxaldehyde 

Relevant articles and documents

Reduction of hERG inhibitory activity in the 4-piperidinyl urea series of H3 antagonists

Structural features of the substituted 4-piperidinyl urea analogs 1, responsible for the H3 antagonist activity, have been identified. Structure-activity relationship of the H3 receptor affinity, hERG ion channel inhibitory activity and their separation is described. Preliminary pharmacokinetic evaluation of the compounds of the series is addressed.