1227068-70-3 Usage
Description
1-(4-(3-chloropyrazin-2-yl)piperidin-1-yl)ethanone, also known as Almorexant, is a chemical compound belonging to the class of piperidine derivatives. It is a selective dual orexin receptor antagonist that targets the orexin OX1 and OX2 receptors in the body, playing a significant role in regulating wakefulness and arousal.
Uses
Used in Pharmaceutical Industry:
Almorexant is used as a therapeutic agent for the treatment of insomnia and other sleep disorders. It functions by blocking the activity of orexin, a neuropeptide that is crucial in regulating the sleep-wake cycle, thus helping to improve sleep quality and duration.
Additionally, Almorexant is being studied for its potential applications in the treatment of other conditions such as addiction and anxiety. However, further research is necessary to fully understand its therapeutic potential and safety profile in these areas.
Check Digit Verification of cas no
The CAS Registry Mumber 1227068-70-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,0,6 and 8 respectively; the second part has 2 digits, 7 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 1227068-70:
(9*1)+(8*2)+(7*2)+(6*7)+(5*0)+(4*6)+(3*8)+(2*7)+(1*0)=143
143 % 10 = 3
So 1227068-70-3 is a valid CAS Registry Number.
1227068-70-3Relevant articles and documents
HETEROARYLOXYCARBOCYCLYL COMPOUNDS AS PDE10 INHIBITORS
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, (2011/12/02)
Heteroaryloxycarbocyclyl compounds of formula (I), and compositions containing them, and processes for preparing such compounds. Provided herein also are methods of treating disorders or diseases treatable by inhibition of PDE10, such as obesity, non-insulin dependent diabetes, schizophrenia, Huntington's Disease, bipolar disorder, obsessive -compulsive disorder, and the like. Formula (I)
