1227148-21-1Relevant articles and documents
Highly Stereoselective Synthesis of trans -Dihydronarciclasine Analogues
Varró, Gábor,Mattyasovszky, Lenke,Grün, Alajos,Simon, András,Hegedüs, László,Kádas, István
, p. 625 - 643 (2018)
Several new trans -dihydronarciclasine analogues were stereo selectively synthesised by applying our feasible and efficient process developed recently. These new phenanthridone alkaloid derivatives were obtained in both racemic and optically active forms. During their enantioselective syntheses, high selectivities (up to 99% ee) were achieved by using (8 S,9 S)-9-amino(9-deoxy)epiquinine as an organocatalyst. The modifications, the introduction of ethoxy or methoxy groups, were made in ring A of the phenanthridone scaffold.
Noyort's Ts-DPEN ligand: Simple yet effective catalyst for the highly enantioselective michael addition of acetone to nitroalkenes
Peng, Lin,Xu, Xiao-Ying,Wang, Liang-Liang,Huang, Jun,Bai, Jian-Fei,Huang, Qing-Chun,Wang, Li-Xin
experimental part, p. 1849 - 1853 (2010/07/18)
Highly enantioselective Michael addition of acetone to a variety of nitroalkenes promoted by simple chiral primary amine bifunctional catalysts (e.g., Noyori's Ts-DPEN ligand) together with terephthalic acid in excellent yields (84-99%) and enantioselectivities (93-98 % ee) is reported.