122715-97-3

Upstream product

• 140-29-4 phenylacetonitrile 
• 3183-15-1 4-oxo-5-phenylvaleric acid 
• 21175-42-8 (±)-5-benzyldihydrofuran-2(3H)-one 
• 300-57-2 allylbenzene 
• 924893-87-8 4-hydroxy-N,N-dimethyl-5-phenylpentanamide 
• 6921-34-2 benzylmagnesium chloride 

Relevant academic research and scientific papers

Lipase-catalyzed kinetic resolution of 2-phenylethanol derivatives and chiral oxa-Pictet-Spengler reaction as the key steps in the synthesis of enantiomerically pure tricyclic amines

A series of 5,6,7,8,9,10-hexahydro-5,9-epoxybenzocycloocten-6-amines have been synthesized and pharmacologically evaluated in receptor binding studies (σ1, σ2, NMDA, κ, and μ receptors). The first key step of the synthesis was a chir

SYNTHESIS OF γ-KETOAMIDES VIA NUCLEOPHILIC ATTACK ON IRON TETRACARBONYL COMPLEXES OF α,β-UNSATURATED AMIDES

Organolithium and Grignard reagents react with the readily-formed iron tetracarbonyl complexes of α,β-unsaturated amides to give γ-ketoamides in good yield via acyl transfer from the metal to the β carbon of the α,β-unsaturated amide.