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1227163-84-9

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1227163-84-9 Usage

General Description

(S)-1-(2-(difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine is a chemical compound with a complex molecular structure. It contains a fluorine atom and a difluoromethyl group attached to a pyridine ring, as well as a pyrimidin-5-yl group attached to a phenyl ring. The compound also features an isoindol-3-amine moiety, which is a bicyclic structure containing an amine group. This chemical may have potential applications in pharmaceutical research and drug development, as it possesses various functional groups and structural features that could interact with biological targets or enzymes. Further study and experimentation may be necessary to fully understand the properties and potential uses of this compound.

Check Digit Verification of cas no

The CAS Registry Mumber 1227163-84-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,2,7,1,6 and 3 respectively; the second part has 2 digits, 8 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1227163-84:
(9*1)+(8*2)+(7*2)+(6*7)+(5*1)+(4*6)+(3*3)+(2*8)+(1*4)=139
139 % 10 = 9
So 1227163-84-9 is a valid CAS Registry Number.

1227163-84-9Downstream Products

1227163-84-9Relevant articles and documents

HEMIFUMARATE SALT

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Page/Page column 11, (2011/11/30)

The present invention relates to a hemifumarate salt of the compound (1S)-1-(2-(difluoromethyl)pyridin-4-yl)-4-fluoro-1-(3-(pyrimidin-5-yl)phenyl)-1H-isoindol-3-amine, Form A thereof and its pharmaceutical compositions. In addition, the present invention relates to therapeutic methods for the treatment and/or prevention of Aβ-related pathologies such as Downs syndrome, β-amyloid angiopathy such as but not limited to cerebral amyloid angiopathy or hereditary cerebral hemorrhage, disorders associated with cognitive impairment such as but not limited to MCI (“mild cognitive impairment”), Alzheimer Disease, memory loss, attention deficit symptoms associated with Alzheimer disease, neurodegeneration associated with diseases such as Alzheimer disease or dementia including dementia of mixed vascular and degenerative origin, pre-senile dementia, senile dementia and dementia associated with Parkinson's disease, progressive supranuclear palsy or cortical basal degeneration.

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