1227264-71-2

Basic information

• Product Name: C₃₃H₃₉NO₈
• Synonyms: C₃₃H₃₉NO₈
• CAS NO: 1227264-71-2
• Molecular Weight: 577.675
• Mol File: 1227264-71-2.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₃₃H₃₉NO₈(CAS DataBase Reference)
• NIST Chemistry Reference: C₃₃H₃₉NO₈(1227264-71-2)
• EPA Substance Registry System: C₃₃H₃₉NO₈(1227264-71-2)

Safety Data

• Hazardous Substances Data: 1227264-71-2(Hazardous Substances Data)

Upstream product

• 1227264-68-7 C₂₁H₂₆O₅ 
• 184363-66-4 (4S)-4-benzyl-3-propionyl-1,3-oxazolidin-2-one 

Downstream Products

• 1227264-73-4 C₃₃H₃₉NO₈ 

Relevant articles and documents

Synthesis of the ABCDEFG ring system of maitotoxin

Maitotoxin (1) continues to fascinate scientists not only because of its size and potent neurotoxicity but also due to its molecular architecture. To provide further support for its structure and facilitate fragment-based biological studies, we developed an efficient chemical synthesis of the ABCDEFG segment 3 of maitotoxin. 13C NMR chemical shift comparisons of synthetic 3 with the corresponding values for the same carbons of maitotoxin revealed a close match, providing compelling evidence for the correctness of the originally assigned structure to this polycyclic system of the natural product. The synthetic strategy for the synthesis of 3 relied heavily on our previously developed furan-based technology involving sequential Noyori asymmetric reduction and Achmatowicz rearrangement for the construction of the required tetrahydropyran building blocks, and employed a B-alkyl Suzuki coupling and a Horner-Wadsworth-Emmons olefination to accomplish their assembly and elaboration to the final target molecule.