1227266-47-8Relevant articles and documents
Synthesis and evaluation of highly potent GABAA receptor antagonists based on gabazine (SR-95531)
Iqbal, Favaad,Ellwood, Ryan,Mortensen, Martin,Smart, Trevor G.,Baker, James R.
, p. 4252 - 4254 (2011)
A selection of highly potent analogues based on the gabazine structure is described. Their syntheses are carried out in just four steps, and their potencies for antagonism at the GABAA receptor were measured. All antagonists showed significantly higher potencies compared to the parent competitive antagonist, gabazine.