122741-65-5Relevant academic research and scientific papers
Asymmetric Total Syntheses of 8,9-Seco-ent-kaurane Diterpenoids Enabled by an Electrochemical ODI-[5+2] Cascade
Ding, Hanfeng,Gao, Beiling,Liu, Zhaobo,Tong, Zhenzhong,Wang, Bingnan
, p. 14892 - 14896 (2021)
An electrochemical ODI-[5+2] cascade reaction was developed which enables the rapid assembly of diversely functionalized bicyclo[3.2.1]octadienones from sensitive ethynylphenols. By combining a directed retro-aldol/aldol process, a [2,3]-sigmatropic rearr
First synthesis of cytotoxic 8,9-secokaurene diterpenoids. An enantioselective route to (-)-O-methylshikoccin and (+)- O-methylepoxyshikoccin
Paquette, Leo A.,Backhaus, Dirk,Braun, Ralf,Underiner, Ted L.,Fuchs, Klaus
, p. 9662 - 9671 (2007/10/03)
A practical route for the total synthesis of 8,9-secokaurene diterpenes is described. The central step is the 3.3]sigmatropic rearrangement of spirocyclic intermediates such as 35, 40, and 41. All three compounds must necessarily respond identically to pr
Terpenoids. XLVIII. New Diterpenoids from Rabdosia shikokiana var. occidentalis
Node, Manabu,Ito, Nozomu,Uchida, Itsuo,Fujita, Eiichi,Fuji, Kaoru
, p. 1029 - 1033 (2007/10/02)
Five new kaurene-type diterpenoids, shikoccin (1), O-methylshikoccin (2), epoxyshikoccin (3), O-methylepoxyshikoccin (4) and shikoccidin (5) were isolated from Rabdosia shikokiana var. occidentalis.All these compounds except for 5 possess a hitherto unknown 8,9-seco-ent-kaurene skeleton.Keywords-Rabdosia shikokiana; diterpenoid; shikoccin; shikoccidin; ent-kaurene; Labiatae
