122744-79-0Relevant articles and documents
Secondary β-Aminobenzamide and Heteroatom Directed Lithiation in the Synthesis of 5,6-Dimethoxyanthanilamides and Related Compounds
Bengtsson, Stefan,Hoegberg, Thomas
, p. 4549 - 4553 (2007/10/02)
Directed ortho-lithiation strategies have been applied in the synthesis of the dopamine D-2 antagonist (S)-6-amino-5-bromo-2,3-dimethoxy-N-benzamide (NCQ 318).The secondary β-amino side chain was found to be a powerful orth