1227486-41-0

Basic information

• Product Name: 4-(6-amino-3-pyridyl)morpholin-3-one
• Synonyms: 4-(6-amino-3-pyridyl)morpholin-3-one
• CAS NO: 1227486-41-0
• Molecular Weight: 193.205
• Mol File: 1227486-41-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 4-(6-amino-3-pyridyl)morpholin-3-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(6-amino-3-pyridyl)morpholin-3-one(1227486-41-0)
• EPA Substance Registry System: 4-(6-amino-3-pyridyl)morpholin-3-one(1227486-41-0)

Safety Data

• Hazardous Substances Data: 1227486-41-0(Hazardous Substances Data)

Upstream product

• 109-11-5 morpholine-3-one 
• 20511-12-0 2-amino-5-iodopyridine 
• 39856-50-3 5-bromo2-nitropyridine 

Relevant articles and documents

TYK2 INHIBITORS AND USES THEREOF

Described herein are compounds that are useful in treating a TYK2-mediated disorder. In some embodiments, the TYK2-mediated disorder is an autoimmune disorder, an inflammatory disorder, a proliferative disorder, an endocrine disorder, a neurological disorder, or a disorder associated with transplantation.

4,6-DIAMINONICOTINAMIDE COMPOUND

[Problem] The present invention provides a 4,6-diaminonicotinamide compound which is useful as an active ingredient of a pharmaceutical composition, in particular, a pharmaceutical composition for treating diseases caused by undesirable and/or abnormal cytokine signal transduction. [Means for Solution] The present inventors have extensively studied compounds having a JAK3 inhibitory action, and as a result, they have found that a 4,6-diaminonicotinamide compound which is the compound of the present invention has an excellent JAK3 inhibitory action and is useful as an agent for preventing or treating diseases caused by undesirable and/or abnormal cytokine signal transduction, thereby completing the present invention.