122749-19-3

Upstream product

• 5949-05-3 (S)-Citronellal 
• 7540-51-4 (S)-3,7-dimethyl-6-octen-1-ol 
• 122749-17-1 (6S)-ethyl 4,4-ethylenedioxy-6-methylnon-8-enoate 
• 109355-81-9 (6S)-ethyl 4,4-ethylenedioxy-7-formyl-6-methylheptanoate 
• 109355-80-8 (6S)-ethyl 4,4-ethylenedioxy-9-hydroxy-6-metylnonanoate 
• 122749-18-2 3-[2-((4E,6E,8E)-(S)-2,8-Dimethyl-deca-4,6,8-trienyl)-[1,3]dioxolan-2-yl]-propionic acid 
• 122749-15-9 (6S)-ethyl 4,4-ethylenedioxy-6,10-dimethylundec-9-enoate 
• 109355-82-0 (6S,8E,10E,12E)-ethyl 4,4-ethylenedioxy-6,12-dimethyltetradeca-8,10,12-trienoate 
• 109463-64-1 (5S,6'S,8'E,10'E,12'E)-1-benzoyl-5-benzyl-3-(4',4'-ethylenedioxy-6',12'-dimethyl-1'-oxotetradeca-8',10',12'-trienyl)-3-phenylselenopyrrolidin-2-one 
• 109463-65-2 (S)-1-Benzoyl-5-benzyl-3-{3-[2-((4E,6E,8E)-(S)-2,8-dimethyl-deca-4,6,8-trienyl)-[1,3]dioxolan-2-yl]-propionyl}-1,5-dihydro-pyrrol-2-one 
• 122749-16-0 (6S)-ethyl 4,4-ethylenedioxy-6-methyl-9-(o-nitrophenylseleno)nonanoate 
• 109355-83-1 (6S,8E,10E,12E)-4,4-ethylenedioxy-1-(imidazol-1-yl)-6,12-dimethyltetradeca-8,10,12-trien-1-one 
• 109355-79-5 (6S)-ethyl 6,10-dimethyl-4-oxoundec-9-enoate 
• 94063-58-8 (5R)-1-benzoyl-5-benzylpyrrolidin-2-one 

Relevant academic research and scientific papers

Cytochalasan synthesis: An alternative approach to cytochalasin H

The oxo ester (8), from the thiazolium salt catalysed conjugate addition of (S)-citronellal to ethyl acrylate, has been used in a synthesis of the cytochalasa-1,18,21 -trione (3). This reacts both regio- and stereo-selectively with methylmagnesium chloride to provide the cytochalasin H precursor (4).