1227619-22-8

Basic information

• Product Name: C₁₈H₂₇BrN₂O₄S
• Synonyms: C₁₈H₂₇BrN₂O₄S
• CAS NO: 1227619-22-8
• Molecular Weight: 447.393
• Mol File: 1227619-22-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₈H₂₇BrN₂O₄S(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₈H₂₇BrN₂O₄S(1227619-22-8)
• EPA Substance Registry System: C₁₈H₂₇BrN₂O₄S(1227619-22-8)

Safety Data

• Hazardous Substances Data: 1227619-22-8(Hazardous Substances Data)

Upstream product

• 22262-60-8 methyl 3-bromo-2-(bromomethyl)propionate 
• 1227619-21-7 N-(2-bromobenzyl)-2-(butylamino)ethanesulfonamide 

Relevant articles and documents

Reagent based DOS: A click, Click, Cyclize strategy to probe chemical space

The synthesis of small organic molecules as probes for discovering new therapeutic agents has been an important aspect of chemical-biology. Herein we report a reagent-based, diversity-oriented synthetic (DOS) strategy to probe chemical and biological space via a Click, Click, Cyclize protocol. In this DOS approach, three sulfonamide linchpins underwent cyclization protocols with a variety of reagents to yield a collection of structurally diverse S-heterocycles. In silico analysis is utilized to evaluate the diversity of the compound collection against chemical space (PC analysis), shape space (PMI) and polar surface area (PSA) calculations.