22262-60-8

Basic information

• Product Name: METHYL 3-BROMO-2-(BROMOMETHYL)PROPIONATE
• Synonyms: Methyl 3-bromo-2-(bromomethyl)propionate 98%;Methyl 3-bromo-2-(bromomethyl)propanoate;METHYL 3-BROMO-2-(BROMOMETHYL)PROPIONATE;3-Bromo-2-(bromomethyl)-propionic acid methyl ester;Methyl 2-bis-(bromomethyl)-acetate;Methyl 3-bromo-2-(bromomethyl)propionate,97%;Methyl bis(bromomethyl)acetate;Methyl 3-broMo-2-(broMoMethyl)propionate, 97% 5GR
• CAS NO: 22262-60-8
• Molecular Formula: C₅H₈Br₂O₂
• Molecular Weight: 259.92
• Product Categories: C2 to C5;Carbonyl Compounds;Esters
• Mol File: 22262-60-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 60-62 °C0.4 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: clear colorless to yellow liquid
• Density: 1.82 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0264mmHg at 25°C
• Refractive Index: n20/D 1.508(lit.)
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: METHYL 3-BROMO-2-(BROMOMETHYL)PROPIONATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 3-BROMO-2-(BROMOMETHYL)PROPIONATE(22262-60-8)
• EPA Substance Registry System: METHYL 3-BROMO-2-(BROMOMETHYL)PROPIONATE(22262-60-8)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 22262-60-8(Hazardous Substances Data)

Usage

Uses

Different sources of media describe the Uses of 22262-60-8 differently. You can refer to the following data:
1. methyl 3-bromo-2-(bromomethyl)propanoate is a useful research chemical.
2. Methyl 3-bromo-2-(bromomethyl)propionate was used in synthesis of sultams and (S)-1-benzyl-3-hydroxypyrrolidine.

Chemical Properties

clear colorless to yellow liquid

InChI:InChI=1/C5H8Br2O2/c1-9-5(8)4(2-6)3-7/h4H,2-3H2,1H3

Upstream product

• 41459-42-1 3-bromo-2-(bromomethyl)propionic acid 
• 74-88-4 methyl iodide 
• 67-56-1 methanol 
• 69193-75-5 chlorure de l'acide bromo-3 bromomethyl-2 propionique 

Downstream Products

• 138625-84-0 methyl 1-benzyl-4-methylhexahydro-1H-1,4-diazepine-6-carboxylate 
• 1057344-02-1 9-[4-(tert-butyl-diphenyl-silanyloxymethyl)-3,3-dimethyl-2-oxo-pyrrolidin-1-yl]-bicyclo[3.3.1]nonane-3-carboxylic acid methyl ester 
• 106023-63-6 3-bromo-2-bromomethyl-propan-1-ol 
• 1820736-58-0 4-(tert-butyl) 6-methyl 1,4-oxazepane-4,6-dicarboxylate 
• 1227619-22-8 C₁₈H₂₇BrN₂O₄S 
• 1227619-29-5 methyl 2-((butyl(2-(N-(4-fluorophenethyl)sulfamoyl)-4-(trifluoromethyl)phenyl)amino)methyl)acrylate 
• 220364-77-2 methyl 1,4-dibenzyl-1,4-diazepane-6-carboxylate 
• 30982-08-2 methyl 2-(1-acetoxymethyl)acrylate 
• 122851-43-8 4-Methyl-5-oxo-2-phenylsulfanylmethyl-nonanedioic acid 9-(3-hydroxy-2,2-dimethyl-propyl) ester 1-methyl ester 

Relevant articles and documents

PHOSPHATE DERIVATIVES AND USE THEREOF

The present invention discloses a compound with the following formula (I), or a tautomer, mesomer, racemate, enantiomer, and diastereoisomer thereof, or a mixture form thereof, or a pharmaceutically acceptable salt thereof, or a prodrug molecule thereof, wherein D is selected from: The invention further discloses the use of the compound in the preparation of drugs for preventing and/or treating cancers, and the use of the compound in the preparation of drugs for inhibiting cancer metastasis. The compound of the present invention can effectively inhibit the proliferation and metastasis of cancer cells by adjusting the acidity of a tumor microenvironment to achieve a better effect in clinical cancer treatment, and has broad application prospects.

Preparation of t-Butyl 2-(Phenylthiomethyl)propenoate, t-Butyl 3-(Phenylthio)-2-(phenylthiomethyl)propenoate and Related Compounds

The preparation of t-butyl 2-(phenylthiomethyl)propenoate, t-butyl and methyl 3-(phenylthio)-2-(phenylthiomethyl)propenoate, the corresponding carboxylic acids, and 3-(phenylthio)-2-(phenylsulfinylmethyl)propenoate from 3-bromo-2-(bromomethyl)propionic acid is described.

PHASE TRANSFER CATALYZED SYNTHESIS OF METHYL α-BROMOMETHYLACRYLATE

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