1227628-99-0

Basic information

• Product Name: methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate
• Synonyms: methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate
• CAS NO: 1227628-99-0
• Molecular Weight: 286.149
• Mol File: 1227628-99-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate(1227628-99-0)
• EPA Substance Registry System: methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate(1227628-99-0)

Safety Data

• Hazardous Substances Data: 1227628-99-0(Hazardous Substances Data)

Upstream product

• 32770-98-2 2-methyl-5-benzothiazolecarxylic acid methyl ester 

Downstream Products

• 1227628-09-2 methyl 2-[(3-carbamoyl-2,4-difluorophenoxy)methyl]-1,3-benzothiazole-5-carboxylate 

Relevant articles and documents

NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF

A benzophenone derivative represented by the following formula: whereinR1 represents, for example, an optionally substituted heterocyclic group, or a substituted phenyl group; Z represents, for example, an alkylene group; R2 represents, for example, a carboxyl group optionally protected with alkyl;R3 represents, for example, an optionally protected hydroxyl group; R4 represents, for example, an optionally substituted cycloalkyloxy group; and R5 represents, for example, a hydrogen atom, ???or a salt thereof has anti-arthritic activity, inhibits bone destruction caused by arthritis, and provides high safety and excellent pharmacokinetics and thus is useful as therapeutic agent for arthritis. These compounds have inhibitory effect on AP-1 activity and are useful as preventive or therapeutic agent for diseases in which excessive expression of AP-1 is involved.