32770-98-2

Basic information

• Product Name: 5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI)
• Synonyms: 5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI);5-Benzothiazolecarboxylic acid, 2-Methyl-, Methyl ester;methyl 2-methylbenzo[d]thiazole-5-carboxylate
• CAS NO: 32770-98-2
• Molecular Formula: C₁₀H₉NO₂S
• Molecular Weight: 207.25
• Product Categories: BENZOTHIAZOLE
• Mol File: 32770-98-2.mol

Chemical Properties

• Melting Point: 96-98 °C(Solv: benzene (71-43-2); ligroine (8032-32-4))
• Boiling Point: 318.9±15.0 °C(Predicted)
• Appearance: /
• Density: 1.291±0.06 g/cm3(Predicted)
• Storage Temp.: Sealed in dry,Room Temperature
• PKA: 0.70±0.10(Predicted)
• CAS DataBase Reference: 5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI)(32770-98-2)
• EPA Substance Registry System: 5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI)(32770-98-2)

Safety Data

• Hazardous Substances Data: 32770-98-2(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
5-Benzothiazolecarboxylic acid, 2-methyl-, methyl ester (8CI, 9CI) is used as an intermediate in the synthesis of various pharmaceuticals for its anti-bacterial and anti-fungal properties. It aids in the development of drugs for the treatment of bacterial and fungal infections, providing a valuable contribution to the healthcare sector.
Used in Agrochemical Industry:
In the agrochemical industry, 5-Benzothiazolecarboxylic acid, 2-methyl-, methyl ester (8CI, 9CI) serves as an intermediate in the synthesis of agrochemicals, helping to develop products that protect crops from bacterial and fungal infections, thereby ensuring better crop yields and food security.
Used in Dye and Pigment Industry:
5-Benzothiazolecarboxylic acid, 2-methyl-, methyl ester (8CI, 9CI) is used as a building block in the production of dyes and pigments. Its unique chemical properties contribute to the creation of a wide range of colors and hues, enhancing the quality and variety of products in this industry.
Used in Fragrance Industry:
5-Benzothiazolecarboxylicacid,2-methyl-,methylester(8CI,9CI) is also utilized in the synthesis of fragrances, where its chemical structure plays a role in creating various scents and aromas. It contributes to the development of new and innovative fragrances for the perfume, cosmetics, and personal care industries.
Used in Polymer Synthesis:
5-Benzothiazolecarboxylic acid, 2-methyl-, methyl ester (8CI, 9CI) is used in the synthesis of various polymers, contributing to the development of new materials with unique properties and applications in various industries, such as plastics, textiles, and coatings.
Used in Organic Chemistry Research:
As a compound of interest in the study of organic chemistry, 5-Benzothiazolecarboxylic acid, 2-methyl-, methyl ester (8CI, 9CI) is used in research to explore its properties, reactions, and potential applications, further expanding the understanding of chemical compounds and their uses.

Upstream product

• 14719-83-6 methyl 3-nitro-4-chlorobenzoate 
• 35350-37-9 methyl 4-[[4-(methoxycarbonyl)-2-nitrophenyl]disulfanyl]-3-nitrobenzoate 
• 108-24-7 acetic anhydride 
• 67-56-1 methanol 
• 24851-69-2 2-methylbenzo[d]thiazole-5-carboxylic acid 
• 63837-11-6 5-bromo-2-methylbenzothiazole 
• 201230-82-2 carbon monoxide 
• 68-12-2 N,N-dimethyl-formamide 
• 2363-16-8 methyl 4-bromo-3-nitrobenzoate 
• 74-11-3 para-chlorobenzoic acid 
• 96-99-1 4-chloro-3-nitrobenzoate 

Downstream Products

• 32770-97-1 (2-methyl-1,3-benzothiazol-5-yl)methanol 
• 58395-68-9 C₁₃H₁₅NO₅S₂ 
• 24851-69-2 2-methylbenzo[d]thiazole-5-carboxylic acid 
• 1227628-99-0 methyl 2-bromomethyl-1,3-benzothiazole-5-carboxylate 
• 103264-09-1 (2-methyl-benzothiazol-5-yl)-acetic acid 
• 103754-68-3 (2-methyl-benzothiazol-5-yl)-acetonitrile 
• 101273-96-5 5-benzoyloxymethyl-2-methyl-benzothiazole 
• 103989-03-3 5-acetoxymethyl-2-methyl-benzothiazole 
• 103205-18-1 5-methoxymethyl-2-methyl-benzothiazole 
• 131868-38-7 diethyl-(2-methyl-benzothiazol-5-ylmethyl)-amine 
• 99849-18-0 5-chloromethyl-2-methyl-benzothiazole 
• 20061-46-5 2-methyl-1,3-benzothiazole-5-carbaldehyde 
• 369649-20-7 C₇₁H₁₂N₂S 

Relevant articles and documents

Discovery of a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide M4 positive allosteric modulator (PAM) chemotype

This Letter details our efforts to discover structurally unique M4 PAMs containing 5,6-heteroaryl ring systems. In an attempt to improve the DMPK profiles of the 2,3-dimethyl-2H-indazole-5-carboxamide and 1-methyl-1H-benzo[d][1,2,3]triazole-6-carboxamide cores, we investigated a plethora of core replacements. This exercise identified a novel 2,3-dimethylimidazo[1,2-a]pyrazine-6-carboxamide core that provided improved M4 PAM activity and CNS penetration.

Catalytic Aerobic Photo-oxidation of a Methyl Group on a Heterocycle to Produce an Aldehyde via Homolytic C-I Bond Cleavage caused by Irradiation with Visible Light

A new catalytic method was developed for photo-oxidizing the methyl group on aromatic heterocycles such as benzothiazole, benzoxazole, and quinoline to produce the corresponding aldehyde. This is the first report of the metal-free catalytic synthesis of benzothiazole-2-carboxaldehydes using molecular oxygen as the terminal oxidant.

PYRAZOLOPYRIDINE PYRAZOLOPYRIMIDINE AND RELATED COMPOUNDS

In one aspect this invention relates generally to compounds of Formula: and sub-formulas thereof, or a tautomer of each thereof, a pharmaceutically acceptable salt of each thereof, or a pharmaceutically acceptable solvate of each of the foregoing, where X1, L1, L3, and R3 are described herein.

INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS

A non-infrared sensitized low silver photographic element with a non-light sensitive layer, preferably an antihalation layer, containing a diphenylaminocyclopentene heptacyanine benzothiazolium infrared dye where the benzothiazolium groups have electron-withdrawing substituents on the phenyl ring and solubilzed alkyl groups on the nitrogen. The infrared dye can be present as a liquid-crystalline dispersion. This class of infrared dyes form J-aggregrated species in a liquid-crystalline or a solid particle dispersion with high IR density and low visible absorbance.

INFRARED DYE FOR SILVER HALIDE-BASED PHOTOGRAPHIC ELEMENTS

A non-infrared sensitized low silver photographic element with a non-light sensitive layer, preferably an antihalation layer, containing a diphenylaminocyclopentene heptacyanine benzothiazolium infrared dye where the benzothiazolium groups have electron-withdrawing substituents on the phenyl ring and solubilzed alkyl groups on the nitrogen. The infrared dye can be present as a liquid-crystalline dispersion. This class of infrared dyes form J-aggregated species in a liquid-crystalline or a solid particle dispersion with high IR density and low visible absorbance.

NOVEL BENSOPHENONE DERIVATIVES OR SALTS THEREOF

A benzophenone derivative represented by the following formula: whereinR1 represents, for example, an optionally substituted heterocyclic group, or a substituted phenyl group; Z represents, for example, an alkylene group; R2 represents, for example, a carboxyl group optionally protected with alkyl;R3 represents, for example, an optionally protected hydroxyl group; R4 represents, for example, an optionally substituted cycloalkyloxy group; and R5 represents, for example, a hydrogen atom, ???or a salt thereof has anti-arthritic activity, inhibits bone destruction caused by arthritis, and provides high safety and excellent pharmacokinetics and thus is useful as therapeutic agent for arthritis. These compounds have inhibitory effect on AP-1 activity and are useful as preventive or therapeutic agent for diseases in which excessive expression of AP-1 is involved.

Synthesis of a new spiropyran based on [60]fullerene unit

A new compound 2: spiropyran with [60]fullerene unit was synthesized and characterized by FT-IR, MALDI-TOF MS, NMR, and UV-Vis spectra.