122795-89-5

Upstream product

• 38184-10-0 phenyl 2,3,4,5-tetra-O-benzyl-1-thio-β-D-glucopyranoside 
• 572-09-8 2,3,4,6-tetra-O-acetyl-α-D-glucopyranosyl bromide 
• 930-69-8 sodium thiophenolate 

Relevant academic research and scientific papers

Compositions and methods for cell transformation

The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglycosylated steroid molecules. Most preferably, exogenous or endogenous nucleic acid is contacted with the cell in the presence of a bile acid (e.g., cholic acid) derivatized with an amine-containing side chain.

Polyamine conjugates for treatment of infection

The present invention relates to methods of preventing or treating an infection or disease caused by an infectious agent. The present invention also relates to the augmentation of the efficacy of existing anti-infective agents by the co-administration of the compounds described herein.

Compositions and methods for cell transformation

The present invention relates to methods and compositions for the transformation of cells. In particular, compositions and methods are disclosed which include combinations of the nucleic acid of interest and polyhydroxylated or polyglycosylated steroid molecules. Most preferably, exogenous or endogenous nucleic acid is contacted with the cell in the presence of a bile acid (e.g., cholic acid) derivatized with an amine-containing side chain.

Glycosylated steroid derivatives for transport across biological membranes and process for making and using same

Novel glycosylated steroid derivatives for facilitating the transport of compounds across biological membranes, either in admixture or as conjugates, are disclosed. A novel process for efficient synthesis of these glycosylated steroid derivatives, using activated glycosyl sulfoxide intermediates is provided. Methods for the permeabilization of membranes and the enhancement of the activity of predetermined compounds are also provided.

Block Synthesis of Oligosaccharides under Mild Conditions

Details on a synthesis of the trisaccharide α-D-Glc(1-->6)-β-D-Glc(1-->6)-D-Glc are reported.The O-glycosidic linkages were constructed using the sulfoxide glycosylation reaction.This approach proves to be a rapid glycosylation method leading to high yield and good selectivity. - Keywords: Oligosaccharides, Phenyl 1-Thioglycoside Sulfoxides