1228000-47-2

Upstream product

• 622-79-7 benzyl azide 
• 14267-92-6 1-chloro-4-pentyne 
• 100-39-0 benzyl bromide 
• 100-46-9 benzylamine 

Relevant academic research and scientific papers

Facile azide formation via diazotransfer reaction in a copper tube flow reactor

A copper tube flow reactor is used in the conversion of primary amines into organic azides using imidazole-1-sulfonyl azide hydrogen sulfate. The catalyst is generated in situ from the metallic copper. The reaction can be quenched in acidic environment or via a cycloaddition of the azides formed with an alkyne. The possibility to perform this azide-alkyne cycloaddition using the copper released from the reactor is demonstrated with the synthesis of both a 1,2,3-triazole derivative of benzylamine and of a more complex BODIPY-DOTA adduct.

IONIC LIQUID MONOMER, POLYMER AND METHOD FOR PRODUCING THE SAME AND CROSSLINKED POLYMER

To provide an ionic liquid monomer that makes it possible to produce a polymer having an ionic liquid portion in the main chain.SOLUTION: The present disclosure provides an ionic liquid monomer represented by general formula (A) (in the general formula (A), R1 and R4 are the same or different to denote a divalent hydrocarbon group, optionally having a functional group excluding an azido group and an alkyne group. R2 and R5 are the same or different to denote a monovalent hydrocarbon group, optionally having a hydrogen atom or a functional group excluding an azido group and an alkyne group. R3 denotes a monovalent hydrocarbon group, optionally having a functional group excluding an azido group and an alkyne group. X- is an anion component).SELECTED DRAWING: None

1-D copper(I) coordination polymer based on bidentate 1,3-dithioether ligand: Novel catalyst for azide-alkyne-cycloaddition (AAC) reaction

A novel 1,3-bis(4-fluorophenylthio)-propane ligand based CuI 1-D polymeric coordination complex having formula ([(CuI)2{ArS(CH2)3SAr}2]n, Ar = 4-F-C6H4) has been synthesized and characterized by 1H NMR, 13C NMR and single crystal XRD techniques. This complex has been employed for the first time as suitable catalyst for base-free one-pot three-component regioselective azide-alkyne cycloaddition (AAC) reaction. A novel 1,2,3-triazole compound with sulfur functionalized pendant arms has also been prepared using our catalytic system in a multicomponent manner via one-pot two-step reaction.

Fe/ppm Cu nanoparticles as a recyclable catalyst for click reactions in water at room temperature

New iron-based nanoparticles doped with ppm levels of CuOAc are capable of catalyzing cycloadditions between alkynes and azides to afford triazole-containing products. These reactions take place in water at ambient temperatures, enabled by the presence of

Copper malonamide complexes and their use in azide-alkyne cycloaddition reactions

We report a rare example of the malonamide functionality being used as a ligand in copper catalysis. We have ligated a homologous series of these O,O-chelating architectures to copper, investigated their structure and exploited them in azide-alkyne cycloa

Oxidative esterification of aldehydes using mesoionic 1,2,3-triazolyl carbene organocatalysts

The synthesis and catalytic activity of a new class of 1,2,3-triazolyl N-heterocyclic carbene organocatalysts is described. These new catalysts chemoselectively facilitate the oxidative esterification of aldehydes. NMR acidity studies show an inverse correlation between triazolium acidity and reactivity. Kinetic studies show that the resting state of the catalyst involves a NHC-aldehyde adduct. A catalytically active intermediate was synthesized and characterized by X-ray diffraction as the initial carbene-aldehyde adduct.

Amphiphilic self-assembled polymeric copper catalyst to parts per million levels: Click chemistry

Self-assembly of copper sulfate and a poly(imidazole-acrylamide) amphiphile provided a highly active, reusable, globular, solid-phase catalyst for click chemistry. The self-assembled polymeric Cu catalyst was readily prepared from poly(N-isopropylacrylami

Direct synthesis of 1,4-disubstituted-5-alumino-1,2,3-triazoles: Copper-catalyzed cycloaddition of organic azides and mixed aluminum acetylides

Chemical Equation Presented Al together now: Aluminotriazoles are obtained in a fully chemo- and regioselective manner by a copper-catalyzed cycloaddition of organic azides with mixed-aluminum acetylides (see scheme). The carbon-aluminum bond, which is unaffected by the first transformation, is still able to react further with different electrophiles.